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  2. PGLYRP2 - peptidoglycan recognition protein 2 Gene

PGLYRP2 - peptidoglycan recognition protein 2 Gene

中文名称:肽聚糖识别蛋白 2

种属: Homo sapiens

同用名: tagL; PGRPL; PGRP-L; PGLYRPL; HMFT0141; TAGL-like; tagl-beta; tagL-alpha

基因 ID: 114770 | 基因类型: protein coding

关于 PGLYRP2

Cytogenetic location: 19p13.12 Genomic coordinates (GRCh38): 19:15,468,645-15,479,501 (from NCBI)

This gene has 4 transcripts (splice variants), 274 orthologues and 3 paralogues. Restricted expression toward liver (RPKM 52.9).

功能概要

该基因编码一种肽聚糖识别蛋白,属于 N-乙酰胞壁酰-L-丙氨酸酰胺酶 2 家族。该蛋白水解细菌细胞壁糖肽中 N-乙酰胞壁酰基残基和 L-氨基酸残基之间的连接,因此可能通过将具有生物活性的肽聚糖消化成无生物活性的片段而发挥清道夫作用。[RefSeq 提供,2011 年 9 月]

This gene encodes a peptidoglycan recognition protein, which belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. This protein hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in Bacterial cell wall glycopeptides, and thus may play a scavenger role by digesting biologically active peptidoglycan into biologically inactive fragments. [provided by RefSeq, Sep 2011]

PGLYRP2 基因产物(2)

mRNA Protein Name
NM_001363546.1 NP_001350475.1 N-acetylmuramoyl-L-alanine amidase isoform 2 precursor
NM_052890.4 NP_443122.3 N-acetylmuramoyl-L-alanine amidase isoform 1 precursor

PGLYRP2 蛋白结构

Amidase_2

Amidase_2: N-acetylmuramoyl-L-alanine amidase (404 - 533)

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  • 576 a.a.
蛋白主名 其他名称

N-acetylmuramoyl-L-alanine amidase

peptidoglycan recognition protein L

重组 PGLYRP2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71844 PGLYRP2/PGRP-L Protein, Human (P.pastoris, His) Q96PD5 (22S-576Q) ≥95%

关联疾病

疾病名称 别名
Cicatricial Entropion
Febrile Seizures, Familial, 4

FEB4

Convulsions, Familial Febrile, 4

Familial Febrile Seizures 4

Familial Febrile Convulsions 4

Meester-Loeys Syndrome

MRLS

Familial Febrile Seizures

Familial Febrile Convulsions

Feb

Febrile Seizures, Familial

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta PGLYRP2 VGNC VGNC:75887
Canis familiaris PGLYRP2 VGNC VGNC:44462
Mus musculus PGLYRP2 MGD MGI:1928099
Bos taurus PGLYRP2 VGNC VGNC:32792
Rattus norvegicus PGLYRP2 RGD RGD:1359183
Felis catus PGLYRP2 VGNC VGNC:64123
Others PGLYRP2 NCBI