1. Gene
  2. Dusp1 - dual specificity phosphatase 1 Gene

Dusp1 - dual specificity phosphatase 1 Gene

种属: Rattus norvegicus

同用名: Mkp1; CL100; MKP-1; 3CH134; Ptpn16

基因 ID: 114856 | 基因类型: protein coding

关于 Dusp1

功能概要

This gene encodes a protein that catalyzes the dephosphorylation and inactivation of MAP kinase, and may be involved in Insulin mediated signalling. [provided by RefSeq, Jul 2008]

Dusp1 基因产物(1)

mRNA Protein Name
NM_053769.4 NP_446221.2 dual specificity protein phosphatase 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables growth factor binding IPI
IPI: 通过物理相互作用推断
18929742 RGD
enables protein tyrosine/threonine phosphatase activity IDA
IDA: 通过直接分析推断
12435803 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to hormone stimulus IEP
IEP: 通过表达模式推断
15358679 RGD
involved in intracellular signal transduction IDA
IDA: 通过直接分析推断
11423551 RGD
involved in negative regulation of DNA biosynthetic process IDA
IDA: 通过直接分析推断
10446064 RGD
involved in negative regulation of ERK1 and ERK2 cascade IMP
IMP: 通过突变表型推断
17437549 RGD
involved in negative regulation of apoptotic process IMP
IMP: 通过突变表型推断
15059639 RGD
involved in positive regulation of apoptotic process IMP
IMP: 通过突变表型推断
9228085 RGD
involved in protein dephosphorylation IDA
IDA: 通过直接分析推断
12435803 RGD
involved in response to cAMP IEP
IEP: 通过表达模式推断
15358679 RGD
involved in response to calcium ion IEP
IEP: 通过表达模式推断
11423551 RGD
involved in response to estradiol IEP
IEP: 通过表达模式推断
8804359 RGD
involved in response to glucocorticoid IEP
IEP: 通过表达模式推断
17403137 RGD
involved in response to hydrogen peroxide IEP
IEP: 通过表达模式推断
7540516 RGD
involved in response to light stimulus IEP
IEP: 通过表达模式推断
15527789 RGD
involved in response to retinoic acid IEP
IEP: 通过表达模式推断
15494319 RGD
involved in response to testosterone IEP
IEP: 通过表达模式推断
8804359 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

dual specificity protein phosphatase 1

3CH134/CL100 PTPase

MAP kinase phosphatase-1

mitogen-activated protein (MAP) kinase phosphatase-1

mitogen-activated protein kinase phosphatase 1

oxidative stress-inducible protein tyrosine phosphatase

protein-tyrosine phosphatase CL100

protein-tyros

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Dusp1 NCBI NCBI:1843