OSBPL5 - oxysterol binding protein like 5 Gene

中文名称：氧固醇结合蛋白样 5

种属: Homo sapiens

同用名: ORP5; OBPH1

关于 OSBPL5

功能概要

该基因编码氧固醇结合蛋白 (OSBP) 家族的一个成员，该家族是一组细胞内脂质受体，在维持体内胆固醇平衡方面发挥着关键作用。大多数成员包含一个 N 端 pleckstrin 同源结构域和一个高度保守的 C 端 OSBP 样甾醇结合结构域。该基因已被证明是印记的，仅在胎盘中优先表达母体等位基因。已经鉴定出编码不同亚型的转录变体。[RefSeq 提供，2010 年 10 月]

This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors that play a key role in the maintenance of Cholesterol balance in the body. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. This gene has been shown to be imprinted, with preferential expression from the maternal allele only in placenta. Transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2010]