2. Gene
  3. Adam19 - a disintegrin and metallopeptidase domain 19 (meltrin beta) Gene

Adam19 - a disintegrin and metallopeptidase domain 19 (meltrin beta) Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: MTLNB; Mltnb; MADDAM

基因 ID: 11492 | 基因类型: protein coding

关于 Adam19

功能概要

This gene encodes a cell surface glycoprotein and member of the ADAM (a disintegrin and metalloproteinase) family of endopeptidases. The encoded protein may play a role in the ectodomain shedding of neuregulin proteins. Homozygous knockout mice for this gene exhibit heart development defects and perinatal lethality. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that undergoes proteolytic processing to generate a mature protein product. [provided by RefSeq, Aug 2015]

Adam19 基因产物(4)

mRNA Protein Name
NM_001291890.1 NP_001278819.1 disintegrin and metalloproteinase domain-containing protein 19 isoform 2
NM_001291891.1 NP_001278820.1 disintegrin and metalloproteinase domain-containing protein 19 isoform 3
NM_001311209.1 NP_001298138.1 disintegrin and metalloproteinase domain-containing protein 19 isoform 4
NM_009616.4 NP_033746.1 disintegrin and metalloproteinase domain-containing protein 19 isoform 1 preproprotein
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables SH3 domain binding IMP
IMP: 通过突变表型推断
12615925 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
10527948 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within heart development IMP
IMP: 通过突变表型推断
14673146 MGI
acts upstream of or within membrane protein ectodomain proteolysis IDA
IDA: 通过直接分析推断
11116142 MGI
acts upstream of or within membrane protein ectodomain proteolysis IMP
IMP: 通过突变表型推断
11116142 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in Golgi apparatus IDA
IDA: 通过直接分析推断
11116142 MGI
NOT located in external side of plasma membrane IDA
IDA: 通过直接分析推断
11116142 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

disintegrin and metalloproteinase domain-containing protein 19

MDC beta

Mel beta

a disintegrin and metalloproteinase domain 19 (meltrin beta)

adamalysin 19

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00275 ADAM19 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18194 Adam19 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24668 Adam19 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Adam19 NCBI NCBI:8728
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