Adora2b - adenosine A2b receptor Gene

中文名称：腺苷 A2 b受体

种属: Mus musculus

同用名: A2b; A2BR; A2BAR; AA2BR; ARA2B

关于 Adora2b

功能概要

该基因编码的蛋白可启动 G 蛋白偶联受体活性。参与突触小泡胞吐的调节。在多个过程的上游或内部起作用，包括 cGMP 介导的信号传导的正向调节；对非抗原刺激的慢性炎症反应的正向调节；和细胞因子产生的正调节。位于 Schaffer 侧支 - CA1 突触；谷氨酸能突触；和质膜。在突触中活跃。以多种结构表达，包括心血管系统；中枢神经系统;眼睛;泌尿生殖系统；和直觉。与人类 ADORA2B（腺苷 A2b 受体）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables G protein-coupled receptor activity. Involved in regulation of synaptic vesicle exocytosis. Acts upstream of or within several processes, including positive regulation of cGMP-mediated signaling; positive regulation of chronic inflammatory response to non-antigenic stimulus; and positive regulation of cytokine production. Located in Schaffer collateral - CA1 synapse; glutamatergic synapse; and plasma membrane. Is active in synapse. Is expressed in several structures, including cardiovascular system; central nervous system; eye; genitourinary system; and gut. Orthologous to human ADORA2B (adenosine A2b receptor). [provided by Alliance of Genome Resources, Apr 2022]