1. Gene
  2. Serpini1 - serpin family I member 1 Gene

Serpini1 - serpin family I member 1 Gene

种属: Rattus norvegicus

同用名: PI-12; raPIT5a

基因 ID: 116459 | 基因类型: protein coding

关于 Serpini1

功能概要

Enables serine-type endopeptidase inhibitor activity. Involved in positive regulation of neuron projection development and regulation of cell adhesion. Predicted to be located in neuronal cell body and secretory granule lumen. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in familial encephalopathy with neuroserpin inclusion bodies. Orthologous to human SERPINI1 (Serpin family I member 1). [provided by Alliance of Genome Resources, Apr 2022]

Serpini1 基因产物(1)

mRNA Protein Name
NM_053779.2 NP_446231.1 neuroserpin precursor
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables serine-type endopeptidase inhibitor activity IDA
IDA: 通过直接分析推断
12438159 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of neuron projection development IDA
IDA: 通过直接分析推断
23825416 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

neuroserpin

peptidase inhibitor 12

protease inhibitor 17

serine (or cysteine) peptidase inhibitor, clade I, member 1

serine (or cysteine) proteinase inhibitor clade member 1

serine (or cysteine) proteinase inhibitor, clade I (neuroserpin), member 1

serine protea

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Serpini1 NCBI NCBI:5274
Mus musculus Serpini1 NCBI NCBI:20713