1. Gene
  2. Ggt1 - gamma-glutamyltransferase 1 Gene

Ggt1 - gamma-glutamyltransferase 1 Gene

种属: Rattus norvegicus

同用名: Ggt; Ggtp; GGLUT

基因 ID: 116568 | 基因类型: protein coding

关于 Ggt1

功能概要

Enables aminoacyltransferase activity. Involved in several processes, including liver development; peptide modification; and response to estradiol. Located in extracellular space. Biomarker of alcohol dependence. Human ortholog(s) of this gene implicated in gamma-glutamyl transpeptidase deficiency. Orthologous to several human genes including GGT1 (gamma-glutamyltransferase 1). [provided by Alliance of Genome Resources, Apr 2022]

Ggt1 基因产物(1)

mRNA Protein Name
NM_053840.2 NP_446292.2 glutathione hydrolase 1 proenzyme
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables aminoacyltransferase activity IDA
IDA: 通过直接分析推断
2567161 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to oxidative stress IEP
IEP: 通过表达模式推断
18075840 RGD
involved in hepatoblast differentiation IEP
IEP: 通过表达模式推断
10934156 RGD
involved in hepatocyte differentiation IEP
IEP: 通过表达模式推断
10934156 RGD
involved in liver regeneration IEP
IEP: 通过表达模式推断
10934156 RGD
involved in peptide modification IDA
IDA: 通过直接分析推断
11601992 RGD
involved in response to alcohol IEP
IEP: 通过表达模式推断
6113606 RGD
involved in response to estradiol IEP
IEP: 通过表达模式推断
18291430 RGD
involved in response to lipopolysaccharide IEP
IEP: 通过表达模式推断
19699728 RGD
involved in response to tumor necrosis factor IEP
IEP: 通过表达模式推断
16973162 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
18291430 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

glutathione hydrolase 1 proenzyme

GGT 1

gamma glutamyl-transferase 1

gamma-glutamyl transpeptidase

gamma-glutamyltranspeptidase 1

leukotriene-C4 hydrolase

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ggt1 NCBI NCBI:2678