2. Gene
  3. LEAP2 - liver enriched antimicrobial peptide 2 Gene

LEAP2 - liver enriched antimicrobial peptide 2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：肝脏富集抗菌肽 2

种属: Homo sapiens

同用名: LEAP-2

基因 ID: 116842 | 基因类型: protein coding

关于 LEAP2

Cytogenetic location: 5q31.1 Genomic coordinates (GRCh38): 5:132,873,668-132,875,046 (from NCBI)

This gene has 3 transcripts (splice variants) and 116 orthologues. Biased expression in liver (RPKM 158.3), small intestine (RPKM 13.5) and 1 other tissue.

功能概要

该基因编码一种富含半胱氨酸的阳离子抗菌肽，主要在肝脏中表达。成熟肽具有抗革兰氏阳性细菌和酵母菌的活性。[RefSeq 提供，2014 年 9 月]

This gene encodes a cysteine-rich cationic antimicrobial peptide that is expressed predominantly in the liver. The mature peptide has activity against gram-positive bacteria and yeasts. [provided by RefSeq, Sep 2014]

LEAP2 基因产物(1)

mRNA Protein Name
NM_052971.3 NP_443203.1 liver-expressed antimicrobial peptide 2 precursor
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in antimicrobial humoral immune response mediated by antimicrobial peptide IMP
IMP: 通过突变表型推断
12493837 GOA
involved in defense response to fungus IMP
IMP: 通过突变表型推断
12493837 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

LEAP2 蛋白结构

LEAP-2

LEAP-2: Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) (1 - 77)

  • 0
  • 77 a.a.
蛋白主名 其他名称

liver-expressed antimicrobial peptide 2

关联疾病

疾病名称 别名
Listeria Meningitis

Meningitis, Listeria
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P5645 LEAP-2 97.64% 否
HY-RS07582 LEAP2 Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus LEAP2 RGD RGD:1561235
Mus musculus LEAP2 MGD MGI:2672795
Canis familiaris LEAP2 VGNC VGNC:42628
Felis catus LEAP2 VGNC VGNC:102242
Bos taurus LEAP2 VGNC VGNC:30831
Macaca mulatta LEAP2 VGNC VGNC:74161
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