2. Gene
  3. Kcnh2 - potassium voltage-gated channel subfamily H member 2 Gene

Kcnh2 - potassium voltage-gated channel subfamily H member 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: ERG1

基因 ID: 117018 | 基因类型: protein coding

关于 Kcnh2

功能概要

Enables inward rectifier Potassium Channel activity and scaffold protein binding activity. Involved in central nervous system development; potassium ion transport; and regulation of membrane potential. Is integral component of plasma membrane. Human ortholog(s) of this gene implicated in long QT syndrome; long QT syndrome 2; and short QT syndrome. Orthologous to human KCNH2 (potassium voltage-gated channel subfamily H member 2). [provided by Alliance of Genome Resources, Apr 2022]

Kcnh2 基因产物(1)

mRNA Protein Name
NM_053949.1 NP_446401.1 potassium voltage-gated channel subfamily H member 2
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables inward rectifier potassium channel activity IDA
IDA: 通过直接分析推断
9664620 RGD
enables monoatomic ion channel activity IDA
IDA: 通过直接分析推断
11804849 RGD
enables potassium channel activity IDA
IDA: 通过直接分析推断
11804849 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
22879586 RGD
enables protein-containing complex binding IDA
IDA: 通过直接分析推断
11212207 RGD
enables scaffold protein binding IPI
IPI: 通过物理相互作用推断
18923542 RGD
enables voltage-gated potassium channel activity IDA
IDA: 通过直接分析推断
15677682 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in potassium ion transport IDA
IDA: 通过直接分析推断
9390998 RGD
involved in regulation of membrane potential IDA
IDA: 通过直接分析推断
11804849 RGD
involved in spinal cord development IEP
IEP: 通过表达模式推断
15365256 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

potassium voltage-gated channel subfamily H member 2

ERG-1

RERG

eag-related protein 1

ether-a-go-go-related gene potassium channel 1

ether-a-go-go-related protein 1

potassium channel, voltage gated eag related subfamily H, member 2

potassium voltage-gated channel, subfamily H (eag-related), member 2

相关产品

Approval
生物活性分子 (2)
目录号 产品名 作用方式
纯度 是否罕见病
HY-B0437 Sotalol hydrochloride 99.93% 否
HY-103196 Sotalol Inhibitor / 否
Pre-clinical Phase
生物活性分子 (7)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-16697 CID 16020046 Antagonist 99.81% 否
HY-N0267 Hypaconitine 99.49% 否
HY-B0437AS Sotalol-d6 hydrochloride 98.01% 否
HY-B0437S Sotalol-d6 Inhibitor / 否
HY-RS07126 KCNH2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS16857 Kcnh2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23298 Kcnh2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Kcnh2 NCBI NCBI:3757
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