2. Gene
  3. Bin1 - bridging integrator 1 Gene

Bin1 - bridging integrator 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 117028 | 基因类型: protein coding

关于 Bin1

功能概要

Enables GTPase binding activity. Involved in positive regulation of GTPase activity; positive regulation of endocytosis; and synaptic vesicle endocytosis. Located in several cellular components, including T-tubule; Z disc; and axon. Is active in glutamatergic synapse. Is extrinsic component of synaptic vesicle membrane. Human ortholog(s) of this gene implicated in breast carcinoma; centronuclear myopathy 2; and prostate adenocarcinoma. Orthologous to human BIN1 (bridging integrator 1). [provided by Alliance of Genome Resources, Apr 2022]

Bin1 基因产物(1)

mRNA Protein Name
NM_053959.2 NP_446411.1 myc box-dependent-interacting protein 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables GTPase binding IPI
IPI: 通过物理相互作用推断
9348539 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
9341169 RGD
enables protein-containing complex binding IPI
IPI: 通过物理相互作用推断
9348539 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of GTPase activity IDA
IDA: 通过直接分析推断
9348539 RGD
involved in positive regulation of endocytosis IMP
IMP: 通过突变表型推断
9348539 RGD
involved in synaptic vesicle endocytosis IDA
IDA: 通过直接分析推断
9348539 RGD
involved in synaptic vesicle endocytosis IMP
IMP: 通过突变表型推断
9348539 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in I band IDA
IDA: 通过直接分析推断
9182667 RGD
located in T-tubule IDA
IDA: 通过直接分析推断
9182667 RGD
located in Z disc IDA
IDA: 通过直接分析推断
9182667 RGD
located in axon initial segment IDA
IDA: 通过直接分析推断
9182667 RGD
located in axon terminus IDA
IDA: 通过直接分析推断
9348539 RGD
located in cerebellar mossy fiber IDA
IDA: 通过直接分析推断
9348539 RGD
is active in extrinsic component of synaptic vesicle membrane IDA
IDA: 通过直接分析推断
9348539 RGD
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
9348539 RGD
located in node of Ranvier IDA
IDA: 通过直接分析推断
9182667 RGD
located in synaptic vesicle IDA
IDA: 通过直接分析推断
9348539 RGD
located in varicosity IDA
IDA: 通过直接分析推断
9348539 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

myc box-dependent-interacting protein 1

Amph2

amphiphysin II

amphiphysin IIamph2

amphiphysin-like protein

相关产品

Pre-clinical Phase
生物活性分子 (20)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-139561 KDM2B-IN-2 99.36% 否
HY-10704 PTP1B-IN-1 Inhibitor 99.65% 否
HY-126246 CDC25B-IN-1 Inhibitor 98.12% 否
HY-139560 KDM2B-IN-1 Inhibitor 99.19% 否
HY-135711 PDE8B-IN-1 / 否
HY-136556 Factor B-IN-1 Inhibitor ≥95.0% 否
HY-147646 CDK1/Cyc B-IN-1 98.47% 否
HY-162811 LAG-3 biner 1 97.08% 否
HY-117848 PDE8B-IN-1 hydrochloride Inhibitor / 否
HY-142957 NaPi2b-IN-1 Inhibitor / 否
HY-145695 Dual AChE-MAO B-IN-1 Inhibitor / 否
HY-147945 DNA gyrase B-IN-1 Inhibitor / 否
HY-163285 PDE3B-IN-1 Inhibitor / 否
HY-168185 α-glucosidase/PTP1B-IN-1 Inhibitor / 否
HY-176762 TOP3B-IN-1 Inhibitor / 否
HY-RS01504 BIN1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-170412 Cox B-IN-1 Inhibitor / 否
HY-170810 E.coli Gyrase B-IN-1 Inhibitor / 否
HY-RS18913 Bin1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25404 Bin1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Bin1 NCBI NCBI:274
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