2. Gene
  3. Park7 - Parkinsonism associated deglycase Gene

Park7 - Parkinsonism associated deglycase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Dj1; CAP1; DJ-1; SP22

基因 ID: 117287 | 基因类型: protein coding

关于 Park7

功能概要

Predicted to enable several functions, including enzyme activator activity; enzyme binding activity; and transition metal ion binding activity. Involved in several processes, including cellular response to lipopolysaccharide; negative regulation of NMDA glutamate receptor activity; and positive regulation of fertilization. Located in several cellular components, including membrane raft; mitochondrion; and sperm head. Used to study Parkinson's disease and Parkinsonism. Biomarker of Parkinsonism. Human ortholog(s) of this gene implicated in Parkinson's disease; Parkinson's disease 7; Parkinsonism; cerebral infarction; and middle cerebral artery infarction. Orthologous to human PARK7 (Parkinsonism associated deglycase). [provided by Alliance of Genome Resources, Apr 2022]

Park7 基因产物(12)

mRNA Protein Name
NM_001277249.1 NP_001264178.1 Parkinson disease protein 7 homolog isoform 1
NM_001277250.1 NP_001264179.1 Parkinson disease protein 7 homolog isoform 2
NM_001277251.1 NP_001264180.1 Parkinson disease protein 7 homolog isoform 2
NM_001277252.1 NP_001264181.1 Parkinson disease protein 7 homolog isoform 2
NM_001277253.1 NP_001264182.1 Parkinson disease protein 7 homolog isoform 2
NM_057143.2 NP_476484.1 Parkinson disease protein 7 homolog isoform 2
NM_001277249.1 NP_001264178.1 Parkinson disease protein 7 homolog isoform 1
NM_001277250.1 NP_001264179.1 Parkinson disease protein 7 homolog isoform 2
NM_001277251.1 NP_001264180.1 Parkinson disease protein 7 homolog isoform 2
NM_001277252.1 NP_001264181.1 Parkinson disease protein 7 homolog isoform 2
NM_001277253.1 NP_001264182.1 Parkinson disease protein 7 homolog isoform 2
NM_057143.2 NP_476484.1 Parkinson disease protein 7 homolog isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
16854843 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to hypoxia IEP
IEP: 通过表达模式推断
29069575 RGD
involved in cellular response to lipopolysaccharide IEP
IEP: 通过表达模式推断
23847046 RGD
involved in maternal process involved in female pregnancy IEP
IEP: 通过表达模式推断
17609507 RGD
involved in negative regulation of NMDA glutamate receptor activity IMP
IMP: 通过突变表型推断
20698836 RGD
involved in negative regulation of smooth muscle cell migration IDA
IDA: 通过直接分析推断
29069575 RGD
involved in negative regulation of vascular associated smooth muscle cell proliferation IDA
IDA: 通过直接分析推断
29069575 RGD
involved in positive regulation of fertilization IMP
IMP: 通过突变表型推断
11780923 RGD
involved in response to oxidative stress IMP
IMP: 通过突变表型推断
16227205 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
17038803 RGD
involved in spermatogenesis IEP
IEP: 通过表达模式推断
11780923 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axon IDA
IDA: 通过直接分析推断
15673657 RGD
located in endoplasmic reticulum IDA
IDA: 通过直接分析推断
31536960 RGD
located in mitochondrion IDA
IDA: 通过直接分析推断
31536960 RGD
located in sperm head IDA
IDA: 通过直接分析推断
11780923 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

Parkinson disease protein 7 homolog

Parkinson disease (autosomal recessive, early onset) 7

contraception-associated protein 1

fertility protein SP22

maillard deglycase

parkinson disease protein 7 homolog

parkinson protein 7

protein DJ-1

protein deglycase DJ-1

protein/nucleic acid de

相关产品

Pre-clinical Phase
生物活性分子 (6)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-163562 JYQ-164 Inhibitor 99.43% 否
HY-163563 JYQ-173 99.78% 否
HY-RS10043 PARK7 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-163564 JYQ-194 98.05% 否
HY-RS17611 Park7 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24071 Park7 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Park7 NCBI NCBI:11315
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