2. Gene
  3. Ank3 - ankyrin 3, epithelial Gene

Ank3 - ankyrin 3, epithelial Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: AnkG; Ank-3; Ankyrin-3; Ankyrin-G; 2900054D09Rik

基因 ID: 11735 | 基因类型: protein coding

关于 Ank3

功能概要

This gene encodes a member of the ankyrin protein family. Ankyrins link integral membrane proteins to the spectrin-based Cytoskeleton. Ankyrin family members share a protein structure which includes three independently folded domains: the N-terminal ankyrin repeat domain, the central spectrin-binding domain, and the C-terminal rod domain. This ankyrin functions as the major ankyrin in the kidney and may play a role in the polarized distribution of many integral membrane proteins to specific subcellular sites. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Ank3 基因产物(9)

mRNA Protein Name
NM_009670.4 NP_033800.2 ankyrin-3 isoform g
NM_146005.3 NP_666117.2 ankyrin-3 isoform b
NM_170687.3 NP_733788.2 ankyrin-3 isoform f
NM_170688.2 NP_733789.1 ankyrin-3 isoform c
NM_170689.2 NP_733790.2 ankyrin-3 isoform d
NM_170690.2 NP_733791.2 ankyrin-3 isoform e
NM_170728.2 NP_733924.2 ankyrin-3 isoform a
NM_170729.2 NP_733925.2 ankyrin-3 isoform h
NM_170730.2 NP_733926.2 ankyrin-3 isoform i
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
14762142 MGI
enables transmembrane transporter binding IPI
IPI: 通过物理相互作用推断
23903368 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within axon guidance IMP
IMP: 通过突变表型推断
15479642 MGI
involved in axonogenesis IMP
IMP: 通过突变表型推断
11724816 MGI
involved in cellular response to magnesium ion IMP
IMP: 通过突变表型推断
23903368 MGI
involved in magnesium ion homeostasis IMP
IMP: 通过突变表型推断
23903368 MGI
involved in negative regulation of delayed rectifier potassium channel activity IMP
IMP: 通过突变表型推断
23903368 MGI
involved in neuronal action potential IMP
IMP: 通过突变表型推断
9832557 MGI
acts upstream of or within protein localization to axon IMP
IMP: 通过突变表型推断
26671463 MGI
involved in protein localization to plasma membrane IDA
IDA: 通过直接分析推断
11724816 MGI
involved in protein localization to plasma membrane IMP
IMP: 通过突变表型推断
16525039 MGI
acts upstream of or within synapse organization IMP
IMP: 通过突变表型推断
15479642 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axon IDA
IDA: 通过直接分析推断
15479642 MGI
located in axon initial segment IDA
IDA: 通过直接分析推断
11724816 MGI
located in axon initial segment IMP
IMP: 通过突变表型推断
25950943 MGI
located in intercalated disc IDA
IDA: 通过直接分析推断
20877009 MGI
located in membrane IDA
IDA: 通过直接分析推断
7615634 MGI
located in node of Ranvier IDA
IDA: 通过直接分析推断
11724816 MGI
located in paranode region of axon IDA
IDA: 通过直接分析推断
20188654 MGI
is active in postsynapse IDA
IDA: 通过直接分析推断
31813652 MGI
is active in postsynaptic density IDA
IDA: 通过直接分析推断
33398084 MGI
located in synapse IDA
IDA: 通过直接分析推断
10995443 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

ankyrin-3

brain-specific ankyrin-G

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00701 ANK3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19574 Ank3 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26071 Ank3 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ank3 NCBI NCBI:288
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z