2. Gene
  3. Apoa2 - apolipoprotein A-II Gene

Apoa2 - apolipoprotein A-II Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Alp-2; Hdl-1; ApoAII; Apoa-2; Apo-AII; ApoA-II

基因 ID: 11807 | 基因类型: protein coding

关于 Apoa2

功能概要

This gene encodes a component of high density lipoproteins (HDL). Mice lacking the encoded protein have low HDL-cholesterol levels, smaller HDL particles, increased clearance of triglyceride-rich lipoproteins and Insulin hypersensitivity. Transgenic mice overexpressing the encoded protein have elevated levels of HDL-cholesterol and show increased susceptibility to atherosclerosis. Alternative splicing of this gene results in multiple variants. [provided by RefSeq, Mar 2015]

Apoa2 基因产物(4)

mRNA Protein Name
NM_001305549.1 NP_001292478.1 apolipoprotein A-II preproprotein
NM_001305550.1 NP_001292479.1 apolipoprotein A-II preproprotein
NM_001305585.1 NP_001292514.1 apolipoprotein A-II preproprotein
NM_013474.2 NP_038502.2 apolipoprotein A-II preproprotein
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables high-density lipoprotein particle binding IMP
IMP: 通过突变表型推断
14729860 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cholesterol homeostasis IDA
IDA: 通过直接分析推断
8422330 MGI
acts upstream of or within cholesterol homeostasis IGI
IGI: 通过遗传相互作用推断
10357838 MGI
acts upstream of or within cholesterol homeostasis IMP
IMP: 通过突变表型推断
10357838 MGI
acts upstream of or within cholesterol metabolic process IGI
IGI: 通过遗传相互作用推断
10357838 MGI
acts upstream of or within cholesterol metabolic process IMP
IMP: 通过突变表型推断
8647961 MGI
acts upstream of or within lipid transport IMP
IMP: 通过突变表型推断
14729860 MGI
acts upstream of or within lipoprotein metabolic process IDA
IDA: 通过直接分析推断
7837794 MGI
acts upstream of or within negative regulation of lipase activity IMP
IMP: 通过突变表型推断
10357838 MGI
acts upstream of or within regulation of intestinal cholesterol absorption IMP
IMP: 通过突变表型推断
8962133 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
1596514 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

apolipoprotein A-II

apolipoprotein A2

重组 Apoa2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P77562 Apolipoprotein A-II/APOA2 Protein, Mouse (HEK293, Fc) P09813 (A19-K102) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS19983 Apoa2 Mouse Pre-designed siRNA Set A / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Apoa2 NCBI NCBI:336
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