1. Gene
  2. Aqp1 - aquaporin 1 Gene

Aqp1 - aquaporin 1 Gene

种属: Mus musculus

同用名: CHIP28

基因 ID: 11826 | 基因类型: protein coding

关于 Aqp1

功能概要

Enables Ephrin Receptor binding activity; potassium ion transmembrane transporter activity; and water transmembrane transporter activity. Involved in defense response to Gram-negative bacterium and potassium ion transport. Acts upstream of or within several processes, including corticotropin secretion; glomerular filtration; and metanephros development. Located in several cellular components, including basolateral plasma membrane; extracellular exosome; and symbiont-containing vacuole. Is integral component of membrane. Is expressed in several structures, including alimentary system; cardiovascular system; genitourinary system; sensory organ; and skeleton. Orthologous to human AQP1 (Aquaporin 1 (Colton blood group)). [provided by Alliance of Genome Resources, Apr 2022]

Aqp1 基因产物(1)

mRNA Protein Name
NM_007472.2 NP_031498.1 aquaporin-1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ephrin receptor binding IPI
IPI: 通过物理相互作用推断
10839360 MGI
enables potassium ion transmembrane transporter activity IDA
IDA: 通过直接分析推断
18665841 MGI
enables water transmembrane transporter activity IDA
IDA: 通过直接分析推断
10644730 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within camera-type eye morphogenesis IMP
IMP: 通过突变表型推断
11891232 MGI
acts upstream of cell migration IMP
IMP: 通过突变表型推断
19298815 MGI
acts upstream of or within corticotropin secretion IMP
IMP: 通过突变表型推断
18511498 MGI
involved in defense response to Gram-negative bacterium IMP
IMP: 通过突变表型推断
18665841 MGI
acts upstream of or within establishment of localization in cell IGI
IGI: 通过遗传相互作用推断
12133842 MGI
acts upstream of or within establishment of localization in cell IMP
IMP: 通过突变表型推断
10613915 MGI
acts upstream of fibroblast migration IMP
IMP: 通过突变表型推断
19298815 MGI
acts upstream of or within glomerular filtration IMP
IMP: 通过突变表型推断
15283758 MGI
involved in lateral ventricle development IEP
IEP: 通过表达模式推断
16133142 MGI
acts upstream of or within lipid digestion IMP
IMP: 通过突变表型推断
11121384 MGI
involved in metanephric descending thin limb development IEP
IEP: 通过表达模式推断
18618131 MGI
involved in metanephric glomerulus vasculature development IEP
IEP: 通过表达模式推断
18618131 MGI
involved in metanephric proximal convoluted tubule segment 2 development IEP
IEP: 通过表达模式推断
18618131 MGI
involved in metanephric proximal straight tubule development IEP
IEP: 通过表达模式推断
18618131 MGI
acts upstream of or within multicellular organismal-level water homeostasis IMP
IMP: 通过突变表型推断
12034763 MGI
acts upstream of or within positive regulation of fibroblast migration IMP
IMP: 通过突变表型推断
19298815 MGI
involved in potassium ion transport IDA
IDA: 通过直接分析推断
18665841 MGI
acts upstream of or within renal water absorption IGI
IGI: 通过遗传相互作用推断
10662735 MGI
acts upstream of or within renal water absorption IMP
IMP: 通过突变表型推断
9468475 MGI
acts upstream of or within secretion by cell IMP
IMP: 通过突变表型推断
18511498 MGI
acts upstream of or within secretory granule organization IMP
IMP: 通过突变表型推断
18511498 MGI
acts upstream of or within sensory perception of pain IMP
IMP: 通过突变表型推断
16476579 MGI
acts upstream of or within water transport IDA
IDA: 通过直接分析推断
10644730 MGI
acts upstream of or within water transport IGI
IGI: 通过遗传相互作用推断
12133842 MGI
acts upstream of or within water transport IMP
IMP: 通过突变表型推断
9886922 MGI
acts upstream of or within wound healing IMP
IMP: 通过突变表型推断
19298815 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in apical plasma membrane IDA
IDA: 通过直接分析推断
16133142 MGI
located in axon IDA
IDA: 通过直接分析推断
17257750 MGI
located in basal plasma membrane IDA
IDA: 通过直接分析推断
23238222 MGI
located in basolateral plasma membrane IDA
IDA: 通过直接分析推断
16133142 MGI
located in brush border IDA
IDA: 通过直接分析推断
16133142 MGI
located in caveola IDA
IDA: 通过直接分析推断
23238222 MGI
located in extracellular exosome IDA
IDA: 通过直接分析推断
19724054 MGI
located in membrane IDA
IDA: 通过直接分析推断
12181190 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
11078688 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

aquaporin-1

AQP-1

DER2

aquaporin-CHIP

delayed early response protein 2

growth factor-induced delayed early response protein

water channel protein for red blood cells and kidney proximal tubule

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Aqp1 NCBI NCBI:358