1. Gene
  2. PSTK - phosphoseryl-tRNA kinase Gene

PSTK - phosphoseryl-tRNA kinase Gene

中文名称:磷酸丝氨酰 tRNA 激酶

种属: Homo sapiens

同用名: C10orf89

基因 ID: 118672 | 基因类型: protein coding

关于 PSTK

Cytogenetic location: 10q26.13 Genomic coordinates (GRCh38): 10:122,980,401-122,990,390 (from NCBI)

This gene has 9 transcripts (splice variants) and 196 orthologues. Ubiquitous expression in bone marrow (RPKM 1.8), testis (RPKM 1.5) and 25 other tissues.

功能概要

预测启用激酶活性和 tRNA 结合活性。预计参与磷酸化;硒代半胱氨酰-tRNA (Sec) 生物合成过程;和翻译。预测作用于硒代半胱氨酸掺入的上游或内部。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable kinase activity and tRNA binding activity. Predicted to be involved in phosphorylation; selenocysteinyl-tRNA(Sec) biosynthetic process; and translation. Predicted to act upstream of or within selenocysteine incorporation. [provided by Alliance of Genome Resources, Apr 2022]

PSTK 基因产物(2)

mRNA Protein Name
NM_001363531.2 NP_001350460.1 L-seryl-tRNA(Sec) kinase isoform 1
NM_153336.3 NP_699167.2 L-seryl-tRNA(Sec) kinase isoform 2

PSTK 蛋白结构

KTI12

KTI12: Chromatin associated protein KTI12 (20 - 57)

KTI12

KTI12: Chromatin associated protein KTI12 (138 - 296)

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  • 300
  • 348 a.a.
蛋白主名 其他名称

L-seryl-tRNA(Sec) kinase

O-phosphoseryl-tRNA(Sec) kinase

关联疾病

疾病名称 别名
Keshan Disease

Caused By Deficiency Of Selenium In The Diet

Enlarged Heart And Poor Heart Function

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta PSTK VGNC VGNC:76335
Mus musculus PSTK MGD MGI:2685945
Bos taurus PSTK VGNC VGNC:33485
Felis catus PSTK VGNC VGNC:64419
Canis familiaris PSTK VGNC VGNC:45126
Rattus norvegicus PSTK RGD RGD:1564300