2. Gene
  3. Atpif1 - ATPase inhibitory factor 1 Gene

Atpif1 - ATPase inhibitory factor 1 Gene

  • 基因
  • 蛋白
  • 相关产品

种属: Mus musculus

同用名: If1; Atpi; IF(1); ATP5IF1

基因 ID: 11983 | 基因类型: protein coding

关于 Atpif1

功能概要

This gene encodes a member of the ATPase inhibitor family of proteins. This protein has been shown to negatively regulate the ATP hydrolysis activity of the F1Fo-ATPase. Knockdown of this gene is associated with reduced heme synthesis in differentiating erythroid cells. Misregulation of this gene has been found to lead to increased aerobic glycolysis in mouse Cancer cells, while high expression levels of this gene have been correlated with gastric and liver Cancer severity in human patients. A pseudogene of this gene has been identified. [provided by RefSeq, Apr 2015]

Atpif1 基因产物(1)

mRNA Protein Name
NM_007512.4 NP_031538.2 ATPase inhibitor, mitochondrial precursor
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
19096392 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in erythrocyte differentiation IMP
IMP: 通过突变表型推断
23135403 MGI
involved in heme biosynthetic process IMP
IMP: 通过突变表型推断
23135403 MGI
acts upstream of or within positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway IMP
IMP: 通过突变表型推断
19096392 MGI
acts upstream of or within reactive oxygen species metabolic process IMP
IMP: 通过突变表型推断
19096392 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

ATPase inhibitor, mitochondrial

ATP synthase F1 subunit epsilon

inhibitor of F(1)F(o)-ATPase

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS01207 ATP5IF1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20209 Atp5if1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26714 Atp5if1 Rat Pre-designed siRNA Set A Pre-designed Set / 否
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