1. Gene
  2. Bach2 - BTB and CNC homology, basic leucine zipper transcription factor 2 Gene

Bach2 - BTB and CNC homology, basic leucine zipper transcription factor 2 Gene

种属: Mus musculus

同用名: E030004N02Rik

基因 ID: 12014 | 基因类型: protein coding

关于 Bach2

功能概要

Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in import into nucleus and negative regulation of transcription by RNA polymerase II. Acts upstream of or within regulation of transcription, DNA-templated. Located in nucleus. Is expressed in several structures, including central nervous system; limb bud; reproductive system; retina; and urinary system. Human ortholog(s) of this gene implicated in immunodeficiency 60. Orthologous to human BACH2 (BTB domain and CNC homolog 2). [provided by Alliance of Genome Resources, Apr 2022]

Bach2 基因产物(1)

mRNA Protein Name
NM_001109661.1 NP_001103131.1 transcription regulator protein BACH2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA binding IDA
IDA: 通过直接分析推断
8887638 MGI
enables DNA-binding transcription factor activity IDA
IDA: 通过直接分析推断
8887638 MGI
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
8887638 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
8887638 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
8887638 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in import into nucleus IMP
IMP: 通过突变表型推断
26021350 MGI
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
8887638 MGI
acts upstream of or within regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
8887638 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
8887638 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

transcription regulator protein BACH2

BTB and CNC homolog 2

BTB and CNC homology 2

Transcription regulator protein BACH2 (BTB and CNC homolog 2)

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Bach2 NCBI NCBI:60468