1. Gene
  2. Bard1 - BRCA1 associated RING domain 1 Gene

Bard1 - BRCA1 associated RING domain 1 Gene

种属: Mus musculus

基因 ID: 12021 | 基因类型: protein coding

关于 Bard1

功能概要

Predicted to enable RNA binding activity; protein heterodimerization activity; and protein homodimerization activity. Predicted to contribute to ubiquitin-protein transferase activity. Predicted to be involved in several processes, including negative regulation of protein export from nucleus; protein K6-linked ubiquitination; and regulation of apoptotic process. Predicted to act upstream of or within DNA repair. Located in nucleus. Is expressed in genitourinary system; limb; and spleen. Used to study breast Cancer. Human ortholog(s) of this gene implicated in breast Cancer and ovarian Cancer. Orthologous to human BARD1 (BRCA1 associated RING domain 1). [provided by Alliance of Genome Resources, Apr 2022]

Bard1 基因产物(1)

mRNA Protein Name
NM_007525.3 NP_031551.1 BRCA1-associated RING domain protein 1
基因本体论
  • 细胞组分
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
11555636 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

BRCA1-associated RING domain protein 1

BARD-1

RING-type E3 ubiquitin transferase BARD1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Bard1 NCBI NCBI:580