2. Gene
  3. Phb2 - prohibitin 2 Gene

Phb2 - prohibitin 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: BAP; REA; Bap37; Bcap37

基因 ID: 12034 | 基因类型: protein coding

关于 Phb2

功能概要

Enables sphingolipid binding activity. Involved in several processes, including CD40 signaling pathway; regulation of gene expression; and regulation of phosphate metabolic process. Acts upstream of or within several processes, including mammary gland development; negative regulation of intracellular Estrogen receptor signaling pathway; and negative regulation of mammary gland epithelial cell proliferation. Located in cell surface; mitochondrial inner membrane; and nucleus. Part of inner mitochondrial membrane protein complex. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; nose; and respiratory system. Orthologous to human PHB2 (prohibitin 2). [provided by Alliance of Genome Resources, Apr 2022]

Phb2 基因产物(1)

mRNA Protein Name
NM_007531.2 NP_031557.2 prohibitin-2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
12878603 MGI
enables sphingolipid binding IDA
IDA: 通过直接分析推断
20959514 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in B cell activation IDA
IDA: 通过直接分析推断
23241883 MGI
acts upstream of estrogen receptor signaling pathway IMP
IMP: 通过突变表型推断
17065319 MGI
acts upstream of or within mammary gland alveolus development IMP
IMP: 通过突变表型推断
17065319 MGI
acts upstream of or within mammary gland branching involved in thelarche IMP
IMP: 通过突变表型推断
17065319 MGI
acts upstream of mammary gland epithelial cell proliferation IMP
IMP: 通过突变表型推断
17065319 MGI
involved in mitophagy IDA
IDA: 通过直接分析推断
28017329 MGI
involved in negative regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
15140878 MGI
acts upstream of or within negative regulation of intracellular estrogen receptor signaling pathway IGI
IGI: 通过遗传相互作用推断
17785450 MGI
acts upstream of or within negative regulation of intracellular estrogen receptor signaling pathway IMP
IMP: 通过突变表型推断
17065319 MGI
acts upstream of or within negative regulation of mammary gland epithelial cell proliferation IMP
IMP: 通过突变表型推断
17065319 MGI
involved in positive regulation of immunoglobulin production IDA
IDA: 通过直接分析推断
23241883 MGI
involved in positive regulation of non-canonical NF-kappaB signal transduction IDA
IDA: 通过直接分析推断
23241883 MGI
acts upstream of or within regulation of branching involved in mammary gland duct morphogenesis IMP
IMP: 通过突变表型推断
17065319 MGI
involved in regulation of cardiolipin metabolic process IMP
IMP: 通过突变表型推断
24856930 MGI
involved in regulation of cytochrome-c oxidase activity IMP
IMP: 通过突变表型推断
20959514 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell surface IDA
IDA: 通过直接分析推断
22417827 MGI
part of inner mitochondrial membrane protein complex IDA
IDA: 通过直接分析推断
24856930 MGI
located in mitochondrial inner membrane IDA
IDA: 通过直接分析推断
11302691 MGI
part of mitochondrial prohibitin complex IPI
IPI: 通过物理相互作用推断
20959514 MGI
located in mitochondrion IDA
IDA: 通过直接分析推断
14651853 MGI
located in nucleus IDA
IDA: 通过直接分析推断
15140878 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

prohibitin-2

B-cell receptor-associated protein 37

B-cell receptor-associated protein BAP37

repressor of estrogen receptor activity

相关产品

Pre-clinical Phase
生物活性分子 (8)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-114989 Fluorizoline Inducer 99.77% 否
HY-152093 YL-939 Inhibitor 99.03% 否
HY-117113 JI051 Inhibitor 98.0% 否
HY-124484 JI130 Inhibitor 99.41% 否
HY-162904 BPU17 98.16% 否
HY-RS16807 Phb2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS10408 PHB2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23247 Phb2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Phb2 NCBI NCBI:11331
Macaca fascicularis Phb2 NCBI NCBI:102136314
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