1. Gene
  2. Bik - BCL2-interacting killer Gene

Bik - BCL2-interacting killer Gene

种属: Mus musculus

同用名: Blk; Nbk; Biklk

基因 ID: 12124 | 基因类型: protein coding

关于 Bik

功能概要

Predicted to enable BH domain binding activity. Acts upstream of or within apoptotic mitochondrial changes; male gonad development; and spermatogenesis. Located in mitochondrial envelope. Is expressed in heart; liver; lung; metanephros; and testis. Human ortholog(s) of this gene implicated in ataxia telangiectasia; breast cancer; colon cancer; and prostate Cancer. Orthologous to human BIK (BCL2 interacting killer). [provided by Alliance of Genome Resources, Apr 2022]

Bik 基因产物(1)

mRNA Protein Name
NM_007546.2 NP_031572.1 bcl-2-interacting killer
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
9525867 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within apoptotic mitochondrial changes IDA
IDA: 通过直接分析推断
9525867 MGI
acts upstream of or within male gonad development IGI
IGI: 通过遗传相互作用推断
16270031 MGI
acts upstream of or within spermatogenesis IGI
IGI: 通过遗传相互作用推断
16270031 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in mitochondrial envelope IDA
IDA: 通过直接分析推断
9525867 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

bcl-2-interacting killer

apoptosis inducer NBK

bik-like killer protein

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Bik NCBI NCBI:638
Rattus norvegicus Bik NCBI NCBI:114496