2. Gene
  3. Bmp7 - bone morphogenetic protein 7 Gene

Bmp7 - bone morphogenetic protein 7 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: OP1

基因 ID: 12162 | 基因类型: protein coding

关于 Bmp7

功能概要

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of Smad Family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. Mutation of this gene results in skeletal, kidney, and Other developmental defects. [provided by RefSeq, Jul 2016]

Bmp7 基因产物(1)

mRNA Protein Name
NM_007557.3 NP_031583.2 bone morphogenetic protein 7 preproprotein
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
12741987 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within BMP signaling pathway IDA
IDA: 通过直接分析推断
14623234 MGI
involved in allantois development IGI
IGI: 通过遗传相互作用推断
10079236 MGI
acts upstream of ameloblast differentiation IDA
IDA: 通过直接分析推断
15525533 MGI
acts upstream of or within anatomical structure formation involved in morphogenesis IMP
IMP: 通过突变表型推断
10049573 MGI
acts upstream of or within animal organ morphogenesis IMP
IMP: 通过突变表型推断
7590254 MGI
acts upstream of or within axon guidance IDA
IDA: 通过直接分析推断
12741987 MGI
acts upstream of or within branching involved in salivary gland morphogenesis IMP
IMP: 通过突变表型推断
11731698 MGI
acts upstream of or within branching morphogenesis of an epithelial tube IDA
IDA: 通过直接分析推断
15831470 MGI
acts upstream of or within camera-type eye morphogenesis IMP
IMP: 通过突变表型推断
16154126 MGI
involved in cardiac muscle tissue development IGI
IGI: 通过遗传相互作用推断
10079236 MGI
involved in cardiac septum morphogenesis IGI
IGI: 通过遗传相互作用推断
10079236 MGI
acts upstream of or within cell development IDA
IDA: 通过直接分析推断
15831470 MGI
acts upstream of cell population proliferation IMP
IMP: 通过突变表型推断
16854970 MGI
involved in chorio-allantoic fusion IGI
IGI: 通过遗传相互作用推断
10079236 MGI
acts upstream of or within embryonic camera-type eye morphogenesis IMP
IMP: 通过突变表型推断
10049573 MGI
acts upstream of or within embryonic limb morphogenesis IGI
IGI: 通过遗传相互作用推断
9664686 MGI
acts upstream of or within embryonic limb morphogenesis IMP
IMP: 通过突变表型推断
9664686 MGI
acts upstream of or within embryonic pattern specification IMP
IMP: 通过突变表型推断
10049573 MGI
acts upstream of or within embryonic skeletal joint morphogenesis IGI
IGI: 通过遗传相互作用推断
9664686 MGI
acts upstream of or within embryonic skeletal joint morphogenesis IMP
IMP: 通过突变表型推断
9664686 MGI
involved in endocardial cushion formation IGI
IGI: 通过遗传相互作用推断
10079236 MGI
acts upstream of or within epithelial cell differentiation IMP
IMP: 通过突变表型推断
17878916 MGI
involved in eye development IMP
IMP: 通过突变表型推断
16154126 MGI
involved in heart trabecula morphogenesis IGI
IGI: 通过遗传相互作用推断
10079236 MGI
involved in hindbrain development IGI
IGI: 通过遗传相互作用推断
10079236 MGI
acts upstream of or within kidney development IMP
IMP: 通过突变表型推断
16154126 MGI
involved in kidney development IMP
IMP: 通过突变表型推断
16154126 MGI
acts upstream of mesenchymal cell apoptotic process involved in nephron morphogenesis IMP
IMP: 通过突变表型推断
9056639 MGI
involved in mesenchyme development IMP
IMP: 通过突变表型推断
9693150 MGI
acts upstream of or within mesoderm formation IGI
IGI: 通过遗传相互作用推断
15843411 MGI
involved in metanephric mesenchymal cell proliferation involved in metanephros development IGI
IGI: 通过遗传相互作用推断
15342483 MGI
involved in metanephric mesenchyme morphogenesis IGI
IGI: 通过遗传相互作用推断
15342483 MGI
acts upstream of or within negative regulation of Notch signaling pathway IGI
IGI: 通过遗传相互作用推断
16324690 MGI
acts upstream of or within negative regulation of cell population proliferation IMP
IMP: 通过突变表型推断
16854970 MGI
acts upstream of or within negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis IMP
IMP: 通过突变表型推断
9056639 MGI
acts upstream of or within negative regulation of neurogenesis IDA
IDA: 通过直接分析推断
17699604 MGI
acts upstream of or within negative regulation of neuron differentiation IMP
IMP: 通过突变表型推断
16325379 MGI
acts upstream of or within negative regulation of prostatic bud formation IDA
IDA: 通过直接分析推断
16324690 MGI
involved in nephrogenic mesenchyme morphogenesis IGI
IGI: 通过遗传相互作用推断
15342483 MGI
involved in neural fold elevation formation IGI
IGI: 通过遗传相互作用推断
10079236 MGI
acts upstream of or within neuron projection morphogenesis IMP
IMP: 通过突变表型推断
16325379 MGI
acts upstream of or within odontogenesis of dentin-containing tooth IDA
IDA: 通过直接分析推断
15525533 MGI
acts upstream of or within pattern specification process IMP
IMP: 通过突变表型推断
7590254 MGI
involved in pericardium morphogenesis IGI
IGI: 通过遗传相互作用推断
10079236 MGI
involved in pharyngeal system development IGI
IGI: 通过遗传相互作用推断
10079236 MGI
acts upstream of or within positive regulation of apoptotic process IMP
IMP: 通过突变表型推断
16854970 MGI
involved in positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis IGI
IGI: 通过遗传相互作用推断
23863481 MGI
acts upstream of or within positive regulation of epithelial cell differentiation IDA
IDA: 通过直接分析推断
15525533 MGI
involved in positive regulation of epithelial to mesenchymal transition IGI
IGI: 通过遗传相互作用推断
23863481 MGI
acts upstream of or within positive regulation of neuron differentiation IDA
IDA: 通过直接分析推断
9786991 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IGI
IGI: 通过遗传相互作用推断
16801560 MGI
acts upstream of or within regulation of branching involved in prostate gland morphogenesis IMP
IMP: 通过突变表型推断
16324690 MGI
acts upstream of or within salivary gland morphogenesis IMP
IMP: 通过突变表型推断
11731698 MGI
acts upstream of or within tube morphogenesis IDA
IDA: 通过直接分析推断
15831470 MGI
involved in ureteric bud development IMP
IMP: 通过突变表型推断
9693150 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
12741987 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

bone morphogenetic protein 7

osteogenic protein 1

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-148234 M4K2234 Inhibitor 98.31% 否
HY-RS01542 BMP7 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17049 Bmp7 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23493 Bmp7 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Bmp7 NCBI NCBI:655
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