2. Gene
  3. Bub1 - BUB1, mitotic checkpoint serine/threonine kinase Gene

Bub1 - BUB1, mitotic checkpoint serine/threonine kinase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Bub1a; D2Xrf87

基因 ID: 12235 | 基因类型: protein coding

关于 Bub1

功能概要

Predicted to enable protein kinase activity. Acts upstream of or within chromosome segregation and positive regulation of intrinsic apoptotic signaling pathway. Located in kinetochore. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in colorectal Cancer. Orthologous to human BUB1 (BUB1 mitotic checkpoint serine/threonine kinase). [provided by Alliance of Genome Resources, Apr 2022]

Bub1 基因产物(2)

mRNA Protein Name
NM_001113179.1 NP_001106650.1 mitotic checkpoint serine/threonine-protein kinase BUB1 isoform 1
NM_009772.2 NP_033902.2 mitotic checkpoint serine/threonine-protein kinase BUB1 isoform 2
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within chromosome segregation IMP
IMP: 通过突变表型推断
17938250 MGI
acts upstream of intrinsic apoptotic signaling pathway IMP
IMP: 通过突变表型推断
17938250 MGI
acts upstream of or within mitotic spindle checkpoint signaling IMP
IMP: 通过突变表型推断
17938250 MGI
acts upstream of or within positive regulation of intrinsic apoptotic signaling pathway IMP
IMP: 通过突变表型推断
17938250 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in chromosome, centromeric region IDA
IDA: 通过直接分析推断
12355205 MGI
located in condensed chromosome, centromeric region IDA
IDA: 通过直接分析推断
18084284 MGI
located in kinetochore IDA
IDA: 通过直接分析推断
15226446 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

mitotic checkpoint serine/threonine-protein kinase BUB1

budding uninhibited by benzimidazoles 1 homolog

mBUB1

相关产品

Pre-clinical Phase
生物活性分子 (12)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-103020 BAY-1816032 Inhibitor 99.73% 否
HY-104001 BAY-524 Inhibitor 99.48% 否
HY-102081 2OH-BNPP1 99.65% 否
HY-104000 BAY-320 Inhibitor 99.74% 否
HY-161865 Antitumor agent-180 Inducer 99.46% 否
HY-172089 TG101209 analog 1 Inducer 98.27% 否
HY-RS01682 BUB1B Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS01681 BUB1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17020 Bub1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19413 Bub1b Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23463 Bub1 Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25905 Bub1b Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Bub1 NCBI NCBI:699
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