2. Gene
  3. Bub1b - BUB1B, mitotic checkpoint serine/threonine kinase Gene

Bub1b - BUB1B, mitotic checkpoint serine/threonine kinase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: BUBR1

基因 ID: 12236 | 基因类型: protein coding

关于 Bub1b

功能概要

Predicted to enable protein kinase activity. Acts upstream of or within metaphase/anaphase transition of mitotic cell cycle and protein localization to chromosome, centromeric region. Located in kinetochore. Part of outer kinetochore. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and sensory organ. Used to study mosaic variegated aneuploidy syndrome 1. Human ortholog(s) of this gene implicated in colorectal Cancer and mosaic variegated aneuploidy syndrome 1. Orthologous to human BUB1B (BUB1 mitotic checkpoint serine/threonine kinase B). [provided by Alliance of Genome Resources, Apr 2022]

Bub1b 基因产物(1)

mRNA Protein Name
NM_009773.3 NP_033903.2 mitotic checkpoint serine/threonine-protein kinase BUB1 beta
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
12925705 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within metaphase/anaphase transition of mitotic cell cycle IGI
IGI: 通过遗传相互作用推断
15767571 MGI
acts upstream of or within protein localization to chromosome, centromeric region IMP
IMP: 通过突变表型推断
19283064 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in kinetochore IDA
IDA: 通过直接分析推断
12925705 MGI
located in kinetochore IMP
IMP: 通过突变表型推断
17227893 MGI
part of outer kinetochore IDA
IDA: 通过直接分析推断
14519686 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

mitotic checkpoint serine/threonine-protein kinase BUB1 beta

MAD3/BUB1-related protein kinase

budding uninhibited by benzimidazoles 1 beta

budding uninhibited by benzimidazoles 1 homolog, beta

mitotic checkpoint kinase MAD3L

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-161865 Antitumor agent-180 Inducer 99.46% 否
HY-RS01682 BUB1B Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-172089 TG101209 analog 1 Inducer 98.27% 否
HY-RS19413 Bub1b Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25905 Bub1b Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Bub1b NCBI NCBI:701
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