1. Gene
  2. Calm2 - calmodulin 2 Gene

Calm2 - calmodulin 2 Gene

种属: Mus musculus

同用名: Cam2; CamC; 1500001E21Rik

基因 ID: 12314 | 基因类型: protein coding

关于 Calm2

功能概要

Enables calcium-dependent protein binding activity. Involved in negative regulation of calcium ion export across plasma membrane and negative regulation of calcium ion transmembrane transporter activity. Acts upstream of or within G2/M transition of mitotic cell cycle and regulation of calcium-mediated signaling. Located in membrane; myelin sheath; and vesicle. Part of voltage-gated Potassium Channel complex. Is expressed in several structures, including alimentary system; metanephros; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in long QT syndrome 15. Orthologous to human CALM2 (Calmodulin 2). [provided by Alliance of Genome Resources, Apr 2022]

Calm2 基因产物(2)

mRNA Protein Name
NM_001355703.1 NP_001342632.1 calmodulin-2 isoform 2
NM_007589.5 NP_031615.1 calmodulin-2 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables calcium-dependent protein binding IPI
IPI: 通过物理相互作用推断
33199372 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
12051765 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within G2/M transition of mitotic cell cycle IDA
IDA: 通过直接分析推断
2469574 MGI
involved in negative regulation of calcium ion export across plasma membrane IDA
IDA: 通过直接分析推断
33199372 MGI
involved in negative regulation of calcium ion transmembrane transporter activity IDA
IDA: 通过直接分析推断
33199372 MGI
involved in presynaptic endocytosis IDA
IDA: 通过直接分析推断
31628181 MGI
involved in presynaptic endocytosis IMP
IMP: 通过突变表型推断
31628181 MGI
acts upstream of or within regulation of calcium-mediated signaling IGI
IGI: 通过遗传相互作用推断
33199372 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in calyx of Held IDA
IDA: 通过直接分析推断
31628181 MGI
is active in calyx of Held IMP
IMP: 通过突变表型推断
31628181 MGI
located in membrane IDA
IDA: 通过直接分析推断
33199372 MGI
located in myelin sheath IDA
IDA: 通过直接分析推断
19855925 MGI
is active in presynaptic cytosol IDA
IDA: 通过直接分析推断
31628181 MGI
is active in presynaptic cytosol IMP
IMP: 通过突变表型推断
31628181 MGI
located in vesicle IDA
IDA: 通过直接分析推断
33199372 MGI
part of voltage-gated potassium channel complex IGI
IGI: 通过遗传相互作用推断
12223552 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

calmodulin-2

caM

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Calm2 NCBI NCBI:805