2. Gene
  3. Camk2b - calcium/calmodulin-dependent protein kinase II, beta Gene

Camk2b - calcium/calmodulin-dependent protein kinase II, beta Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: CaMKII

基因 ID: 12323 | 基因类型: protein coding

关于 Camk2b

功能概要

Enables calmodulin-dependent protein kinase activity. Involved in regulation of neuron migration. Acts upstream of or within several processes, including activation of meiosis involved in egg activation; modulation of chemical synaptic transmission; and protein phosphorylation. Located in cytosol; postsynaptic density; and spindle midzone. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; sensory organ; and skeletal musculature. Human ortholog(s) of this gene implicated in autosomal dominant mental retardation 54. Orthologous to human CAMK2B (calcium/Calmodulin dependent protein kinase II beta). [provided by Alliance of Genome Resources, Apr 2022]

Camk2b 基因产物(3)

mRNA Protein Name
NM_001174053.1 NP_001167524.1 calcium/calmodulin-dependent protein kinase type II subunit beta isoform 1
NM_001174054.1 NP_001167525.1 calcium/calmodulin-dependent protein kinase type II subunit beta isoform 3
NM_007595.5 NP_031621.3 calcium/calmodulin-dependent protein kinase type II subunit beta isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables calcium/calmodulin-dependent protein kinase activity IDA
IDA: 通过直接分析推断
9882483 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
22579289 MGI
enables protein serine/threonine kinase activity IDA
IDA: 通过直接分析推断
19332541 MGI
enables protein serine/threonine kinase activity IMP
IMP: 通过突变表型推断
12660151 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within G1/S transition of mitotic cell cycle IMP
IMP: 通过突变表型推断
12660151 MGI
acts upstream of or within activation of meiosis involved in egg activation IMP
IMP: 通过突变表型推断
9882483 MGI
acts upstream of apoptotic signaling pathway IDA
IDA: 通过直接分析推断
17367784 MGI
acts upstream of or within calcium ion transport IMP
IMP: 通过突变表型推断
12660151 MGI
acts upstream of or within inhibitory G protein-coupled receptor phosphorylation IDA
IDA: 通过直接分析推断
19332541 MGI
acts upstream of or within neuromuscular process controlling balance IMP
IMP: 通过突变表型推断
19503086 MGI
acts upstream of or within peptidyl-serine phosphorylation IDA
IDA: 通过直接分析推断
19332541 MGI
acts upstream of or within positive regulation of apoptotic signaling pathway IDA
IDA: 通过直接分析推断
17367784 MGI
acts upstream of or within protein autophosphorylation IMP
IMP: 通过突变表型推断
12660151 MGI
acts upstream of or within regulation of long-term neuronal synaptic plasticity IMP
IMP: 通过突变表型推断
19503086 MGI
involved in regulation of neuron migration IMP
IMP: 通过突变表型推断
29100089 MGI
acts upstream of or within regulation of synaptic transmission, cholinergic IMP
IMP: 通过突变表型推断
19332541 MGI
acts upstream of or within response to cadmium ion IDA
IDA: 通过直接分析推断
17367784 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytosol IDA
IDA: 通过直接分析推断
9882483 MGI
located in postsynaptic density IDA
IDA: 通过直接分析推断
17114649 MGI
located in spindle midzone IDA
IDA: 通过直接分析推断
9882483 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

calcium/calmodulin-dependent protein kinase type II subunit beta

CaMK II

caM kinase II subunit beta

caMK-II subunit beta

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS01857 CAMK2B Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20531 Camk2b Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27040 Camk2b Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Camk2b NCBI NCBI:816
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