1. Gene
  2. Cap1 - CAP, adenylate cyclase-associated protein 1 (yeast) Gene

Cap1 - CAP, adenylate cyclase-associated protein 1 (yeast) Gene

种属: Mus musculus

基因 ID: 12331 | 基因类型: protein coding

关于 Cap1

功能概要

The product of this gene plays a role in regulating actin dynamics by binding actin monomers and promoting the turnover of actin filaments. Reduced expression of this gene causes a reduction in actin filament turnover rates, causing multiple defects, including an increase in cell size, stress-fiber alterations, and defects in endocytosis and cell motility. A pseudogene of this gene is found on chromosome 14. Alternative splicing results in multiple transcript variants, but does not affect the protein. [provided by RefSeq, Jul 2014]

Cap1 基因产物(4)

mRNA Protein Name
NM_001301067.2 NP_001287996.1 adenylyl cyclase-associated protein 1
NM_001358035.1 NP_001344964.1 adenylyl cyclase-associated protein 1
NM_001358036.1 NP_001344965.1 adenylyl cyclase-associated protein 1
NM_007598.5 NP_031624.2 adenylyl cyclase-associated protein 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
15102471 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within actin cytoskeleton organization IMP
IMP: 通过突变表型推断
15004221 MGI
acts upstream of or within ameboidal-type cell migration IMP
IMP: 通过突变表型推断
15004221 MGI
acts upstream of or within cell morphogenesis IGI
IGI: 通过遗传相互作用推断
7691848 MGI
involved in modification of postsynaptic actin cytoskeleton IDA
IDA: 通过直接分析推断
36264429 MGI
involved in modification of postsynaptic actin cytoskeleton IMP
IMP: 通过突变表型推断
36264429 MGI
acts upstream of or within receptor-mediated endocytosis IMP
IMP: 通过突变表型推断
15004221 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cortical actin cytoskeleton IDA
IDA: 通过直接分析推断
15004221 MGI
located in cytoplasm IDA
IDA: 通过直接分析推断
7691848 MGI
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
36264429 MGI
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
36264429 MGI
is active in postsynapse IDA
IDA: 通过直接分析推断
36264429 MGI
is active in postsynapse IMP
IMP: 通过突变表型推断
36264429 MGI
is active in presynapse IDA
IDA: 通过直接分析推断
36264429 MGI
is active in presynapse IMP
IMP: 通过突变表型推断
36264429 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

adenylyl cyclase-associated protein 1

adenylyl cyclase-associated CAP protein, yeast homolog 1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cap1 NCBI NCBI:10487
Rattus norvegicus Cap1 NCBI NCBI:64185