Casp12 - caspase 12 Gene

中文名称：半胱天冬酶 12

种属: Mus musculus

关于 Casp12

功能概要

该基因编码的蛋白可启动半胱氨酸型内肽酶活性。参与响应内质网应激和自身蛋白水解的内在凋亡信号通路。作用于凋亡过程和内质网未折叠蛋白反应的上游或内部。位于内质网。以多种结构表达，包括消化系统；脑;心血管系统;泌尿生殖系统；和免疫系统。与人类 CASP12（caspase 12（基因/假基因））同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables cysteine-type endopeptidase activity. Involved in intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress and self proteolysis. Acts upstream of or within apoptotic process and endoplasmic reticulum unfolded protein response. Located in endoplasmic reticulum. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and immune system. Orthologous to human CASP12 (Caspase 12 (gene/pseudogene)). [provided by Alliance of Genome Resources, Apr 2022]