1. Gene
  2. Cav2 - caveolin 2 Gene

Cav2 - caveolin 2 Gene

种属: Mus musculus

基因 ID: 12390 | 基因类型: protein coding

关于 Cav2

功能概要

This gene belongs to the caveolin family whose members encode the major protein components of caveolae, which are invaginations of plasma membrane. This gene is located adjacent to caveolin-1 and the proteins coexpressed by the two genes localize together in caveolae, where they form hetero-oligomers. The encoded protein may be involved in diverse cellular functions including proliferation, differentiation, endocytosis and trafficking. Alternative splicing of this gene results in transcript variants encoding different isoforms. [provided by RefSeq, Apr 2013]

Cav2 基因产物(2)

mRNA Protein Name
NM_001277756.1 NP_001264685.1 caveolin-2 isoform 2
NM_016900.4 NP_058596.1 caveolin-2 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables molecular adaptor activity IDA
IDA: 通过直接分析推断
12091389 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
17715130 MGI
enables protein heterodimerization activity IPI
IPI: 通过物理相互作用推断
9361015 MGI
enables protein kinase binding IDA
IDA: 通过直接分析推断
12091389 MGI
enables protein kinase binding IPI
IPI: 通过物理相互作用推断
12091389 MGI
enables protein-macromolecule adaptor activity IDA
IDA: 通过直接分析推断
12091389 MGI
enables scaffold protein binding IPI
IPI: 通过物理相互作用推断
12091389 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within basement membrane organization IMP
IMP: 通过突变表型推断
11884617 MGI
acts upstream of cell population proliferation IMP
IMP: 通过突变表型推断
17200204 MGI
acts upstream of or within endoplasmic reticulum organization IMP
IMP: 通过突变表型推断
17200204 MGI
acts upstream of endothelial cell proliferation IGI
IGI: 通过遗传相互作用推断
21832243 MGI
acts upstream of endothelial cell proliferation IMP
IMP: 通过突变表型推断
11884617 MGI
acts upstream of or within mitochondrion organization IMP
IMP: 通过突变表型推断
17200204 MGI
acts upstream of or within negative regulation of endothelial cell proliferation IMP
IMP: 通过突变表型推断
11884617 MGI
acts upstream of or within negative regulation of skeletal muscle cell proliferation IMP
IMP: 通过突变表型推断
17200204 MGI
acts upstream of or within negative regulation of transforming growth factor beta receptor signaling pathway IGI
IGI: 通过遗传相互作用推断
21832243 MGI
acts upstream of or within positive regulation of endothelial cell proliferation IGI
IGI: 通过遗传相互作用推断
21832243 MGI
acts upstream of skeletal muscle cell proliferation IMP
IMP: 通过突变表型推断
17200204 MGI
acts upstream of or within skeletal muscle fiber development IMP
IMP: 通过突变表型推断
17200204 MGI
acts upstream of transforming growth factor beta receptor signaling pathway IGI
IGI: 通过遗传相互作用推断
21832243 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in acrosomal membrane IDA
IDA: 通过直接分析推断
19144954 MGI
located in caveola IDA
IDA: 通过直接分析推断
11884617 MGI
part of caveolar macromolecular signaling complex IDA
IDA: 通过直接分析推断
11884617 MGI
colocalizes with focal adhesion IDA
IDA: 通过直接分析推断
12091389 MGI
located in membrane IDA
IDA: 通过直接分析推断
11316799 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
11884617 MGI
part of protein-containing complex IDA
IDA: 通过直接分析推断
12091389 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

caveolin-2

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cav2 NCBI NCBI:858