2. Gene
  3. CMKLR1 - chemerin chemokine-like receptor 1 Gene

CMKLR1 - chemerin chemokine-like receptor 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：凯莫瑞趋化因子样受体 1

种属: Homo sapiens

同用名: DEZ; RVER1; ChemR23; CHEMERINR

基因 ID: 1240 | 基因类型: protein coding

关于 CMKLR1

Cytogenetic location: 12q23.3 Genomic coordinates (GRCh38): 12:108,288,046-108,339,311 (from NCBI)

This gene has 6 transcripts (splice variants), 333 orthologues and 8 paralogues. Broad expression in spleen (RPKM 14.3), placenta (RPKM 10.1) and 22 other tissues.

功能概要

启用脂肪动力学激素结合活性和脂肪动力学激素受体活性。涉及多个过程，包括 NF-kappaB 转录因子活性的负调节；巨噬细胞趋化性的正向调节；和调节钙介导的信号。位于质膜。 [由基因组资源联盟提供，2022 年 4 月]

Enables adipokinetic hormone binding activity and adipokinetic hormone receptor activity. Involved in several processes, including negative regulation of NF-kappaB transcription factor activity; positive regulation of macrophage chemotaxis; and regulation of calcium-mediated signaling. Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

CMKLR1 基因产物(4)

mRNA Protein Name
NM_001142343.2 NP_001135815.1 chemerin-like receptor 1 isoform a
NM_001142344.2 NP_001135816.1 chemerin-like receptor 1 isoform a
NM_001142345.2 NP_001135817.1 chemerin-like receptor 1 isoform a
NM_004072.3 NP_004063.1 chemerin-like receptor 1 isoform b
蛋白主名 其他名称

chemerin-like receptor 1

G-protein coupled receptor ChemR23

关联疾病

疾病名称 别名
Monckeberg Arteriosclerosis

Monckeberg Medial Calcific Sclerosis
Cardiovascular Syphilis

Syphilis, Cardiovascular
Hepatic Adenomas, Familial

Hepatic Adenoma, Somatic

Familial Hepatic Adenoma

Familial Liver Cell Adenomas

Liver Cell Adenomas, Familial

Hepatic Adenomas Familial

HEPAF

Ha

Hepatocellular Adenomas

Hepatocellular Adenoma
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-138097 α-NETA ≥98.0% 否
HY-P1844A Chemerin-9 (149-157) (TFA) 99.15% 否
HY-156460 CMKLR1 antagonist 1 / 否
HY-P1844 Chemerin-9 (149-157) / 否
HY-RS02860 CMKLR1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus CMKLR1 VGNC VGNC:60999
Macaca mulatta CMKLR1 VGNC VGNC:99920
Bos taurus CMKLR1 VGNC VGNC:52753
Canis familiaris CMKLR1 VGNC VGNC:39378
Rattus norvegicus CMKLR1 RGD RGD:69359
Mus musculus CMKLR1 MGD MGI:109603
Others CMKLR1 NCBI
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