2. Gene
  3. Cd247 - CD247 antigen Gene

Cd247 - CD247 antigen Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Cd3; T3z; Cd3h; Cd3z; Tcrk; Tcrz; Cd3-eta; Cd3zeta; Cd3-zeta; 4930549J05Rik; A430104F18Rik

基因 ID: 12503 | 基因类型: protein coding

关于 Cd247

功能概要

Predicted to enable identical protein binding activity and protein tyrosine kinase binding activity. Acts upstream of or within T cell receptor signaling pathway and positive regulation of protein localization to cell surface. Located in Golgi apparatus and plasma membrane. Part of alpha-beta T cell receptor complex. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Human ortholog(s) of this gene implicated in immunodeficiency 25. Orthologous to human CD247 (CD247 molecule). [provided by Alliance of Genome Resources, Apr 2022]

Cd247 基因产物(4)

mRNA Protein Name
NM_001113391.2 NP_001106862.1 CD247 antigen isoform zeta precursor
NM_001113392.2 NP_001106863.1 CD247 antigen isoform iota precursor
NM_001113393.2 NP_001106864.2 CD247 antigen isoform theta precursor
NM_031162.4 NP_112439.1 CD247 antigen isoform eta precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
8196616 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within T cell receptor signaling pathway IDA
IDA: 通过直接分析推断
11435465 MGI
acts upstream of or within interleukin-2 production IGI
IGI: 通过遗传相互作用推断
15184345 MGI
acts upstream of or within positive regulation of protein localization to cell surface IDA
IDA: 通过直接分析推断
15184345 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in Golgi apparatus IDA
IDA: 通过直接分析推断
24638062 MGI
part of alpha-beta T cell receptor complex IDA
IDA: 通过直接分析推断
9064344 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
24638062 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

CD247 antigen

CD3 antigen, zeta polypeptide

CD3-zeta/eta

T-cell receptor T3 eta chain

T-cell surface glycoprotein CD3 zeta chain

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS02214 CD247 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21508 Cd247 Mouse Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cd247 NCBI NCBI:919
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