Cebpb - CCAAT/enhancer binding protein (C/EBP), beta Gene

种属: Mus musculus

同用名: LAP; LIP; CRP2; NF-M; Nfil6; NF-IL6; IL-6DBP; C/EBPbeta

基因 ID: 12608 | 基因类型: protein coding

关于 Cebpb

功能概要

Enables several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II core promoter sequence-specific DNA binding activity; and enzyme binding activity. Contributes to RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including liver development; regulation of leukocyte differentiation; and response to bacterium. Acts upstream of or within several processes, including mammary gland epithelium development; positive regulation of osteoblast differentiation; and regulation of gene expression. Located in chromosome; cytoplasm; and nuclear matrix. Part of RNA polymerase II transcription regulator complex. Is expressed in several structures, including adrenal gland; alimentary system; extraembryonic component; genitourinary system; and integumental system. Used to study cleidocranial dysplasia and viral infectious disease. Orthologous to human CEBPB (CCAAT enhancer binding protein beta). [provided by Alliance of Genome Resources, Apr 2022]

Cebpb 基因产物(3)

mRNA	Protein	Name
NM_001287738.1	NP_001274667.1	CCAAT/enhancer-binding protein beta isoform b
NM_001287739.1	NP_001274668.1	CCAAT/enhancer-binding protein beta isoform c
NM_009883.4	NP_034013.1	CCAAT/enhancer-binding protein beta isoform a

基因本体论

分子功能
生物过程
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables DNA binding	IDA IDA: 通过直接分析推断	10510303	MGI
enables DNA-binding transcription activator activity, RNA polymerase II-specific	IDA IDA: 通过直接分析推断	10588870	MGI
contributes to DNA-binding transcription factor activity, RNA polymerase II-specific	IDA IDA: 通过直接分析推断	27812542	MGI
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IDA IDA: 通过直接分析推断	19641492	MGI
contributes to RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA IDA: 通过直接分析推断	27812542	MGI
enables RNA polymerase II core promoter sequence-specific DNA binding	IDA IDA: 通过直接分析推断	25472717	MGI
enables chromatin DNA binding	IDA IDA: 通过直接分析推断	25921091	MGI
enables chromatin binding	IDA IDA: 通过直接分析推断	21122806	MGI
enables histone acetyltransferase binding	IPI IPI: 通过物理相互作用推断	17301242	MGI
enables histone deacetylase binding	IPI IPI: 通过物理相互作用推断	18486321	MGI
enables identical protein binding	IPI IPI: 通过物理相互作用推断	12177065	MGI
enables kinase binding	IPI IPI: 通过物理相互作用推断	10635333	MGI
enables protein binding	IPI IPI: 通过物理相互作用推断	11684016	MGI
enables sequence-specific DNA binding	IDA IDA: 通过直接分析推断	10588870	MGI
enables transcription cis-regulatory region binding	IDA IDA: 通过直接分析推断	24216764	MGI
enables ubiquitin-like protein ligase binding	IPI IPI: 通过物理相互作用推断	24061474	MGI

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in T-helper 1 cell activation	IMP IMP: 通过突变表型推断	17911624	MGI
involved in brown fat cell differentiation	IMP IMP: 通过突变表型推断	19641492	MGI
acts upstream of or within cellular response to amino acid stimulus	IDA IDA: 通过直接分析推断	20548288	MGI
involved in defense response to bacterium	IMP IMP: 通过突变表型推断	17911624	MGI
acts upstream of or within embryonic placenta development	IGI IGI: 通过遗传相互作用推断	15509779	MGI
acts upstream of or within fat cell differentiation	IDA IDA: 通过直接分析推断	15509789	MGI
acts upstream of or within fat cell differentiation	IGI IGI: 通过遗传相互作用推断	17888405	MGI
involved in granuloma formation	IMP IMP: 通过突变表型推断	17911624	MGI
involved in hepatocyte proliferation	IDA IDA: 通过直接分析推断	10635333	MGI
involved in intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	IMP IMP: 通过突变表型推断	9531536	MGI
involved in liver regeneration	IMP IMP: 通过突变表型推断	9727068	MGI
acts upstream of or within mammary gland epithelial cell differentiation	IMP IMP: 通过突变表型推断	10707954	MGI
acts upstream of or within mammary gland epithelial cell proliferation	IMP IMP: 通过突变表型推断	10683373	MGI
acts upstream of or within negative regulation of DNA-templated transcription	IDA IDA: 通过直接分析推断	15175325	MGI
involved in negative regulation of T cell proliferation	IDA IDA: 通过直接分析推断	16585579	MGI
acts upstream of or within negative regulation of neuron apoptotic process	IDA IDA: 通过直接分析推断	11684016	MGI
acts upstream of or within neuron differentiation	IDA IDA: 通过直接分析推断	11733516	MGI
involved in ovarian follicle development	IMP IMP: 通过突变表型推断	9303532	MGI
acts upstream of or within positive regulation of DNA-templated transcription	IDA IDA: 通过直接分析推断	15870285	MGI
involved in positive regulation of cold-induced thermogenesis	IMP IMP: 通过突变表型推断	15762841	MGI
involved in positive regulation of fat cell differentiation	IMP IMP: 通过突变表型推断	19324970	MGI
involved in positive regulation of inflammatory response	IGI IGI: 通过遗传相互作用推断	26526992	MGI
involved in positive regulation of interleukin-4 production	IDA IDA: 通过直接分析推断	16585579	MGI
acts upstream of or within positive regulation of osteoblast differentiation	IDA IDA: 通过直接分析推断	15175325	MGI
involved in positive regulation of transcription by RNA polymerase II	EXP EXP: 通过实验结果推断	11792321	MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II	IDA IDA: 通过直接分析推断	10859308	MGI
involved in positive regulation of transcription by RNA polymerase II	IDA IDA: 通过直接分析推断	18486321	MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II	IGI IGI: 通过遗传相互作用推断	22078933	MGI
involved in positive regulation of transcription by RNA polymerase II	IMP IMP: 通过突变表型推断	25472717	MGI
involved in regulation of dendritic cell differentiation	IGI IGI: 通过遗传相互作用推断	26526992	MGI
acts upstream of or within regulation of interleukin-6 production	IDA IDA: 通过直接分析推断	11976687	MGI
involved in regulation of osteoclast differentiation	IDA IDA: 通过直接分析推断	19440205	MGI
involved in regulation of transcription by RNA polymerase II	IMP IMP: 通过突变表型推断	19324970	MGI
involved in response to lipopolysaccharide	IMP IMP: 通过突变表型推断	17724128	MGI
acts upstream of transcription by RNA polymerase II	IDA IDA: 通过直接分析推断	10859308	MGI
acts upstream of transcription by RNA polymerase II	IGI IGI: 通过遗传相互作用推断	22078933	MGI

细胞组分 GO 注释	逻辑证据	参考文献	来源
part of C/EBP complex	IPI IPI: 通过物理相互作用推断	17264204	MGI
part of RNA polymerase II transcription regulator complex	EXP EXP: 通过实验结果推断	11792321	MGI
part of RNA polymerase II transcription regulator complex	IDA IDA: 通过直接分析推断	27812542	MGI
located in chromatin	IDA IDA: 通过直接分析推断	15187136	MGI
located in condensed chromosome, centromeric region	IDA IDA: 通过直接分析推断	21122806	MGI
located in cytoplasm	IDA IDA: 通过直接分析推断	11684016	MGI
located in nuclear matrix	IDA IDA: 通过直接分析推断	21122806	MGI
located in nucleus	IDA IDA: 通过直接分析推断	10588870	MGI

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

蛋白主名

其他名称

CCAAT/enhancer-binding protein beta

AGP/EBP	C/EBP BETA
interleukin-6-dependent-binding protein	liver-enriched transcriptional activator
nuclear protein Il6

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS02446	CEBPB Human Pre-designed siRNA Set A	Pre-designed Set	/	否
HY-RS17419	Cebpb Mouse Pre-designed siRNA Set A	Pre-designed Set	/	否
HY-RS23873	Cebpb Rat Pre-designed siRNA Set A	Pre-designed Set	/	否

直系同源

种属	基因名	来源	基因 ID
Homo sapiens	Cebpb	NCBI	NCBI:1051

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站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

Cebpb - CCAAT/enhancer binding protein (C/EBP), beta Gene

关于 Cebpb

功能概要

Cebpb 基因产物(3)

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Cebpb - CCAAT/enhancer binding protein (C/EBP), beta Gene

关于 Cebpb

功能概要

Cebpb 基因产物(3)

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z