2. Gene
  3. Cflar - CASP8 and FADD-like apoptosis regulator Gene

Cflar - CASP8 and FADD-like apoptosis regulator Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Cash; Flip; MRIT; CLARP; FLAME; Casper; Gm9845; c-Flip; FLAME-1; I-FLICE; 2310024N18Rik; A430105C05Rik

基因 ID: 12633 | 基因类型: protein coding

关于 Cflar

功能概要

Enables peptidase activator activity. Involved in several processes, including negative regulation of myoblast fusion; positive regulation of NF-kappaB transcription factor activity; and skeletal muscle atrophy. Acts upstream of or within negative regulation of programmed cell death and response to bacterium. Located in cytoplasm. Is expressed in several structures, including central nervous system; gut; heart; peripheral nervous system ganglion; and retina. Orthologous to human CFLAR (CASP8 and FADD like Apoptosis regulator). [provided by Alliance of Genome Resources, Apr 2022]

Cflar 基因产物(6)

mRNA Protein Name
NM_001289704.3 NP_001276633.1 CASP8 and FADD-like apoptosis regulator isoform 1
NM_001293804.2 NP_001280733.1 CASP8 and FADD-like apoptosis regulator isoform 4
NM_001293805.2 NP_001280734.1 CASP8 and FADD-like apoptosis regulator isoform 4
NM_001355056.1 NP_001341985.1 CASP8 and FADD-like apoptosis regulator isoform 4
NM_009805.4 NP_033935.2 CASP8 and FADD-like apoptosis regulator isoform 2
NM_207653.6 NP_997536.1 CASP8 and FADD-like apoptosis regulator isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables peptidase activator activity IDA
IDA: 通过直接分析推断
21368763 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
21368763 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of apoptotic process IMP
IMP: 通过突变表型推断
16263940 MGI
acts upstream of necroptotic process IGI
IGI: 通过遗传相互作用推断
21368763 MGI
acts upstream of or within negative regulation of apoptotic process IMP
IMP: 通过突变表型推断
16263940 MGI
acts upstream of or within negative regulation of cysteine-type endopeptidase activity involved in apoptotic process IMP
IMP: 通过突变表型推断
16263940 MGI
acts upstream of or within negative regulation of extrinsic apoptotic signaling pathway IGI
IGI: 通过遗传相互作用推断
22675671 MGI
involved in negative regulation of myoblast fusion IMP
IMP: 通过突变表型推断
21364645 MGI
acts upstream of or within negative regulation of necroptotic process IGI
IGI: 通过遗传相互作用推断
21368763 MGI
involved in positive regulation of NF-kappaB transcription factor activity IMP
IMP: 通过突变表型推断
21364645 MGI
involved in regulation of skeletal muscle satellite cell proliferation IMP
IMP: 通过突变表型推断
21364645 MGI
acts upstream of or within response to bacterium IEP
IEP: 通过表达模式推断
23012479 MGI
involved in skeletal muscle atrophy IMP
IMP: 通过突变表型推断
21364645 MGI
involved in skeletal muscle tissue development IMP
IMP: 通过突变表型推断
21364645 MGI
involved in skeletal muscle tissue regeneration IMP
IMP: 通过突变表型推断
21364645 MGI
involved in skeletal myofibril assembly IMP
IMP: 通过突变表型推断
21364645 MGI
involved in wound healing IMP
IMP: 通过突变表型推断
21364645 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
16263940 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

CASP8 and FADD-like apoptosis regulator

FADD-like antiapoptotic molecule 1

MACH-related inducer of toxicity

caspase homolog

caspase-eight-related protein

caspase-like apoptosis regulatory protein

cellular FLICE-like inhibitory protein

inhibitor of FLICE

usurpin

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS02570 CFLAR Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21525 Cflar Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28043 Cflar Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cflar NCBI NCBI:8837
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z