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  3. Chat - choline acetyltransferase Gene

Chat - choline acetyltransferase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: CHOACTase; B230380D24Rik

基因 ID: 12647 | 基因类型: protein coding

关于 Chat

功能概要

Enables choline O-acetyltransferase activity. Acts upstream of or within several processes, including adult walking behavior; establishment of synaptic specificity at neuromuscular junction; and rhythmic excitation. Located in axon; cytoplasm; and neuronal cell body. Is expressed in several structures, including alimentary system; cranium; heart; nervous system; and retina. Used to study congenital myasthenic syndrome 6. Human ortholog(s) of this gene implicated in Alzheimer's disease and congenital myasthenic syndrome 6. Orthologous to human CHAT (choline O-acetyltransferase). [provided by Alliance of Genome Resources, Apr 2022]

Chat 基因产物(1)

mRNA Protein Name
NM_009891.2 NP_034021.1 choline O-acetyltransferase
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables choline O-acetyltransferase activity IMP
IMP: 通过突变表型推断
12441053 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within adult walking behavior IMP
IMP: 通过突变表型推断
15820692 MGI
acts upstream of or within chemical synaptic transmission IMP
IMP: 通过突变表型推断
12533614 MGI
acts upstream of or within dendrite development IMP
IMP: 通过突变表型推断
12441053 MGI
acts upstream of or within establishment of synaptic specificity at neuromuscular junction IMP
IMP: 通过突变表型推断
12533614 MGI
acts upstream of or within muscle organ development IMP
IMP: 通过突变表型推断
12441053 MGI
acts upstream of or within neuromuscular synaptic transmission IMP
IMP: 通过突变表型推断
12441053 MGI
acts upstream of or within neuron differentiation IMP
IMP: 通过突变表型推断
12441053 MGI
acts upstream of or within rhythmic behavior IMP
IMP: 通过突变表型推断
15820692 MGI
acts upstream of or within rhythmic excitation IMP
IMP: 通过突变表型推断
15820692 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axon IDA
IDA: 通过直接分析推断
19906978 MGI
located in cytoplasm IDA
IDA: 通过直接分析推断
24462097 MGI
located in neuron projection IDA
IDA: 通过直接分析推断
12115678 MGI
located in neuronal cell body IDA
IDA: 通过直接分析推断
9853118 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

choline O-acetyltransferase

choline acetylase

相关产品

Approval
生物活性分子 (1)
目录号 产品名 作用方式
纯度 是否罕见病
HY-B0764 Bucladesine sodium 99.48% 是
Pre-clinical Phase
生物活性分子 (9)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-N7038 Phytohemagglutinin 80.00% 否
HY-N8376 Fustin 99.52% 否
HY-159904 ChAT IN-1 Inhibitor 98.51% 否
HY-N0801 Polygalacic acid Inhibitor 98.92% 否
HY-131574 Heliosupine N-oxide Inhibitor / 否
HY-RS02597 CHAT Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS12824 SH2D3C Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22115 Chat Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28637 Chat Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Chat NCBI NCBI:1103
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