2. Gene
  3. Chrm1 - cholinergic receptor, muscarinic 1, CNS Gene

Chrm1 - cholinergic receptor, muscarinic 1, CNS Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: M1; M1R; Chrm-1

基因 ID: 12669 | 基因类型: protein coding

关于 Chrm1

功能概要

Enables neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential. Acts upstream of or within regulation of locomotion. Located in cholinergic synapse. Is active in Schaffer collateral - CA1 synapse. Is integral component of postsynaptic membrane. Is expressed in central nervous system; retina; and urinary system. Human ortholog(s) of this gene implicated in Lambert-Eaton myasthenic syndrome; asthma; and myasthenia gravis. Orthologous to human CHRM1 (cholinergic receptor muscarinic 1). [provided by Alliance of Genome Resources, Apr 2022]

Chrm1 基因产物(2)

mRNA Protein Name
NM_001112697.1 NP_001106167.1 muscarinic acetylcholine receptor M1
NM_007698.3 NP_031724.2 muscarinic acetylcholine receptor M1
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in postsynaptic modulation of chemical synaptic transmission EXP
EXP: 通过实验结果推断
26472558 MGI
involved in postsynaptic modulation of chemical synaptic transmission IDA
IDA: 通过直接分析推断
26472558 MGI
involved in postsynaptic modulation of chemical synaptic transmission IMP
IMP: 通过突变表型推断
26472558 MGI
acts upstream of or within regulation of locomotion IMP
IMP: 通过突变表型推断
11752469 MGI
involved in regulation of postsynaptic membrane potential EXP
EXP: 通过实验结果推断
26472558 MGI
involved in regulation of postsynaptic membrane potential IDA
IDA: 通过直接分析推断
26472558 MGI
involved in regulation of postsynaptic membrane potential IMP
IMP: 通过突变表型推断
26472558 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in Schaffer collateral - CA1 synapse EXP
EXP: 通过实验结果推断
26472558 MGI
is active in Schaffer collateral - CA1 synapse IDA
IDA: 通过直接分析推断
26472558 MGI
is active in Schaffer collateral - CA1 synapse IMP
IMP: 通过突变表型推断
26472558 MGI
is active in cholinergic synapse IDA
IDA: 通过直接分析推断
20335477 MGI
is active in postsynaptic membrane IDA
IDA: 通过直接分析推断
20335477 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

muscarinic acetylcholine receptor M1

AChR M1

m1 muscarinic acetylcholine receptor protein

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-N0735 Phellodendrine chloride 99.79% 否
HY-N0427 Phellodendrine 99.60% 否
HY-RS02660 CHRM1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18169 Chrm1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24643 Chrm1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Chrm1 NCBI NCBI:1128
Rattus norvegicus Chrm1 NCBI NCBI:25229
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