2. Gene
  3. Vsx2 - visual system homeobox 2 Gene

Vsx2 - visual system homeobox 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: or; Chx10; Hox10; Hox-10

基因 ID: 12677 | 基因类型: protein coding

关于 Vsx2

功能概要

This gene encodes a member of the Vsx (visual system homeobox) family which belongs to the larger PRD homeobox class. The encoded protein is required for eye organogenesis and controls retinal development. Disruption of this gene is associated with ocular retardation J (orJ), a mouse disease which causes microphthalmia, retinal degeneration and optic nerve aplasia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014]

Vsx2 基因产物(2)

mRNA Protein Name
NM_001301427.1 NP_001288356.1 visual system homeobox 2 isoform 1
NM_007701.3 NP_031727.1 visual system homeobox 2 isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
9464541 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within camera-type eye development IGI
IGI: 通过遗传相互作用推断
15576400 MGI
acts upstream of or within cell fate commitment IMP
IMP: 通过突变表型推断
15576400 MGI
acts upstream of cell population proliferation IMP
IMP: 通过突变表型推断
8630490 MGI
acts upstream of or within negative regulation of neuroblast proliferation IMP
IMP: 通过突变表型推断
16384989 MGI
acts upstream of neuroblast proliferation IMP
IMP: 通过突变表型推断
16384989 MGI
acts upstream of or within positive regulation of cell population proliferation IMP
IMP: 通过突变表型推断
8630490 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
15767664 MGI
acts upstream of or within retina morphogenesis in camera-type eye IMP
IMP: 通过突变表型推断
8630490 MGI
acts upstream of or within retinal bipolar neuron differentiation IMP
IMP: 通过突变表型推断
8630490 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
15767664 MGI
located in intracellular anatomical structure IDA
IDA: 通过直接分析推断
10482234 MGI
located in nucleus IDA
IDA: 通过直接分析推断
15767664 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

visual system homeobox 2

C. elegans ceh-10 homeo domain containing homolog

ceh-10 homeodomain-containing homolog

homeobox protein CHX10

ocular retardation

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-W009310 9-cis-Retinal 99.9% 否
HY-RS15719 VSX2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19973 Vsx2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26476 Vsx2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Vsx2 NCBI NCBI:338917
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