2. Gene
  3. Cnga3 - cyclic nucleotide gated channel alpha 3 Gene

Cnga3 - cyclic nucleotide gated channel alpha 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: CNG3

基因 ID: 12790 | 基因类型: protein coding

关于 Cnga3

功能概要

Enables intracellular cyclic nucleotide activated cation channel activity. Acts upstream of or within retinal cone cell development. Located in photoreceptor outer segment and plasma membrane. Is expressed in eye; gut; and male reproductive gland or organ. Used to study achromatopsia 2. Human ortholog(s) of this gene implicated in achromatopsia 2 and color blindness. Orthologous to human CNGA3 (cyclic nucleotide gated channel subunit alpha 3). [provided by Alliance of Genome Resources, Apr 2022]

Cnga3 基因产物(2)

mRNA Protein Name
NM_001282010.1 NP_001268939.1 cyclic nucleotide-gated cation channel alpha-3 isoform 1
NM_009918.2 NP_034048.1 cyclic nucleotide-gated cation channel alpha-3 isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables intracellularly cyclic nucleotide-activated monoatomic cation channel activity IPI
IPI: 通过物理相互作用推断
10662822 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
10662822 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within retina development in camera-type eye IGI
IGI: 通过遗传相互作用推断
21124780 MGI
acts upstream of or within retinal cone cell development IMP
IMP: 通过突变表型推断
21052544 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cone photoreceptor outer segment IDA
IDA: 通过直接分析推断
10813773 MGI
located in photoreceptor outer segment IDA
IDA: 通过直接分析推断
15634774 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
10813773 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

cyclic nucleotide-gated cation channel alpha-3

CNG channel alpha-3

CNG-3

cone photoreceptor cGMP-gated channel subunit alpha

cyclic nucleotide-gated channel subunit alpha 3

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS02881 CNGA3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22449 Cnga3 Mouse Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cnga3 NCBI NCBI:1261
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