2. Gene
  3. Col11a1 - collagen, type XI, alpha 1 Gene

Col11a1 - collagen, type XI, alpha 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: cho; C530001D20Rik

基因 ID: 12814 | 基因类型: protein coding

关于 Col11a1

功能概要

This gene encodes the alpha-1 subunit of type XI Collagen, one of the low abundance fibrillar collagens that is essential for normal embryonic skeletal development and the cohesive properties of cartilage. The encoded protein, in association with the alpha-1 subunit of type II Collagen, forms a heterotrimeric type XI procollagen that undergoes proteolytic processing. Mice lacking the encoded protein develop severe chondrodysplasia and die at birth. [provided by RefSeq, Dec 2015]

Col11a1 基因产物(1)

mRNA Protein Name
NM_007729.3 NP_031755.2 collagen alpha-1(XI) chain preproprotein
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cartilage condensation IMP
IMP: 通过突变表型推断
3070812 MGI
acts upstream of or within cartilage development IMP
IMP: 通过突变表型推断
886247 MGI
acts upstream of or within chondrocyte development IMP
IMP: 通过突变表型推断
4100752 MGI
acts upstream of or within collagen fibril organization IGI
IGI: 通过遗传相互作用推断
17029294 MGI
acts upstream of or within collagen fibril organization IMP
IMP: 通过突变表型推断
3070812 MGI
acts upstream of or within embryonic skeletal system morphogenesis IMP
IMP: 通过突变表型推断
4100752 MGI
acts upstream of or within heart morphogenesis IGI
IGI: 通过遗传相互作用推断
17029294 MGI
acts upstream of or within inner ear morphogenesis IMP
IMP: 通过突变表型推断
1952599 MGI
acts upstream of or within proteoglycan metabolic process IMP
IMP: 通过突变表型推断
3070812 MGI
acts upstream of or within skeletal system morphogenesis IMP
IMP: 通过突变表型推断
7859283 MGI
acts upstream of or within tendon development IGI
IGI: 通过遗传相互作用推断
21467034 MGI
acts upstream of or within tendon development IMP
IMP: 通过突变表型推断
21467034 MGI
acts upstream of or within ventricular cardiac muscle tissue morphogenesis IMP
IMP: 通过突变表型推断
17029294 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of collagen trimer IDA
IDA: 通过直接分析推断
17683922 MGI
located in extracellular matrix IDA
IDA: 通过直接分析推断
17029294 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

collagen alpha-1(XI) chain

a1(XI) collagen

pro-alpha1(XI) collagen

procollagen, type XI, alpha 1

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS02960 COL11A1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19540 Col11a1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26036 Col11a1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Col11a1 NCBI NCBI:1301
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