1. Gene
  2. Col4a4 - collagen, type IV, alpha 4 Gene

Col4a4 - collagen, type IV, alpha 4 Gene

种属: Mus musculus

同用名: [a]4(IV); E130010M05Rik

基因 ID: 12829 | 基因类型: protein coding

关于 Col4a4

功能概要

An extracellular matrix structural constituent. Acts upstream of or within glomerular basement membrane development. Located in basement membrane. Part of Collagen type IV trimer. Is expressed in glomerular tuft and testis. Used to study autosomal recessive Alport syndrome. Human ortholog(s) of this gene implicated in autosomal recessive Alport syndrome; benign familial hematuria; and end stage renal disease. Orthologous to human COL4A4 (Collagen type IV alpha 4 chain). [provided by Alliance of Genome Resources, Apr 2022]

Col4a4 基因产物(1)

mRNA Protein Name
NM_007735.2 NP_031761.1 collagen alpha-4(IV) chain precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables extracellular matrix structural constituent IPI
IPI: 通过物理相互作用推断
7962065 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within glomerular basement membrane development IMP
IMP: 通过突变表型推断
10534397 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in basement membrane IDA
IDA: 通过直接分析推断
9264260 MGI
part of collagen type IV trimer IDA
IDA: 通过直接分析推断
7962065 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

collagen alpha-4(IV) chain

procollagen, type IV, alpha 4

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Col4a4 NCBI NCBI:1286