2. Gene
  3. Col6a1 - collagen, type VI, alpha 1 Gene

Col6a1 - collagen, type VI, alpha 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Col6a-1

基因 ID: 12833 | 基因类型: protein coding

关于 Col6a1

功能概要

Predicted to enable Collagen binding activity and platelet-derived growth factor binding activity. Acts upstream of or within cellular response to amino acid stimulus. Located in extracellular matrix and sarcolemma. Is expressed in several structures, including alimentary system; brain; genitourinary system; heart and pericardium; and sensory organ. Used to study Bethlem myopathy and Ullrich congenital muscular dystrophy. Human ortholog(s) of this gene implicated in Ullrich congenital muscular dystrophy. Orthologous to human COL6A1 (Collagen type VI alpha 1 chain). [provided by Alliance of Genome Resources, Apr 2022]

Col6a1 基因产物(1)

mRNA Protein Name
NM_009933.4 NP_034063.1 collagen alpha-1(VI) chain precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
23300779 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within 2-oxoglutarate metabolic process IMP
IMP: 通过突变表型推断
23437220 MGI
acts upstream of or within adipose tissue development IMP
IMP: 通过突变表型推断
19114551 MGI
acts upstream of or within apoptotic nuclear changes IMP
IMP: 通过突变表型推断
14625552 MGI
acts upstream of or within apoptotic process IGI
IGI: 通过遗传相互作用推断
19293339 MGI
acts upstream of or within apoptotic process IMP
IMP: 通过突变表型推断
14625552 MGI
acts upstream of or within autophagy IMP
IMP: 通过突变表型推断
21037586 MGI
acts upstream of or within basement membrane organization IMP
IMP: 通过突变表型推断
25158062 MGI
acts upstream of or within bone development IMP
IMP: 通过突变表型推断
22448243 MGI
acts upstream of or within bone mineralization IMP
IMP: 通过突变表型推断
19248115 MGI
acts upstream of or within canonical Wnt signaling pathway IMP
IMP: 通过突变表型推断
25989472 MGI
acts upstream of or within cartilage development IMP
IMP: 通过突变表型推断
19248115 MGI
acts upstream of or within caveola assembly IMP
IMP: 通过突变表型推断
19114551 MGI
acts upstream of or within cell death IMP
IMP: 通过突变表型推断
28043812 MGI
acts upstream of or within cell morphogenesis IMP
IMP: 通过突变表型推断
24302007 MGI
acts upstream of or within cellular response to amino acid stimulus IDA
IDA: 通过直接分析推断
20548288 MGI
acts upstream of or within circadian rhythm IMP
IMP: 通过突变表型推断
26945058 MGI
acts upstream of or within collagen fibril organization IGI
IGI: 通过遗传相互作用推断
28604699 MGI
acts upstream of or within collagen fibril organization IMP
IMP: 通过突变表型推断
25158062 MGI
acts upstream of or within collagen metabolic process IMP
IMP: 通过突变表型推断
22343710 MGI
acts upstream of or within energy homeostasis IMP
IMP: 通过突变表型推断
19114551 MGI
acts upstream of or within energy reserve metabolic process IMP
IMP: 通过突变表型推断
23437220 MGI
acts upstream of or within extracellular matrix assembly IMP
IMP: 通过突变表型推断
19114551 MGI
acts upstream of or within fat cell proliferation IMP
IMP: 通过突变表型推断
19114551 MGI
acts upstream of or within gene expression IMP
IMP: 通过突变表型推断
19114551 MGI
acts upstream of or within glycolytic process IMP
IMP: 通过突变表型推断
23437220 MGI
acts upstream of or within hair follicle development IDA
IDA: 通过直接分析推断
25989472 MGI
acts upstream of or within hair follicle development IMP
IMP: 通过突变表型推断
25989472 MGI
acts upstream of or within heart development IMP
IMP: 通过突变表型推断
22343710 MGI
acts upstream of or within homeostasis of number of cells IMP
IMP: 通过突变表型推断
28043812 MGI
acts upstream of or within inflammatory response IMP
IMP: 通过突变表型推断
19114551 MGI
acts upstream of or within insulin receptor signaling pathway IMP
IMP: 通过突变表型推断
19114551 MGI
acts upstream of or within insulin-like growth factor receptor signaling pathway IMP
IMP: 通过突变表型推断
28043812 MGI
acts upstream of or within limb joint morphogenesis IMP
IMP: 通过突变表型推断
22448243 MGI
acts upstream of or within lung alveolus development IMP
IMP: 通过突变表型推断
31837950 MGI
acts upstream of or within lung development IMP
IMP: 通过突变表型推断
24357721 MGI
acts upstream of or within lung epithelial cell differentiation IMP
IMP: 通过突变表型推断
31837950 MGI
acts upstream of or within lung morphogenesis IMP
IMP: 通过突变表型推断
31837950 MGI
acts upstream of or within metabolic process IMP
IMP: 通过突变表型推断
23437220 MGI
acts upstream of or within mitochondrial depolarization IGI
IGI: 通过遗传相互作用推断
19293339 MGI
acts upstream of or within mitochondrial depolarization IMP
IMP: 通过突变表型推断
19519726 MGI
acts upstream of or within mitochondrial transmembrane transport IMP
IMP: 通过突变表型推断
19519726 MGI
acts upstream of or within mitochondrion organization IGI
IGI: 通过遗传相互作用推断
19293339 MGI
acts upstream of or within mitochondrion organization IMP
IMP: 通过突变表型推断
14625552 MGI
acts upstream of or within multicellular organismal locomotion IMP
IMP: 通过突变表型推断
19114551 MGI
acts upstream of or within muscle cell apoptotic process IMP
IMP: 通过突变表型推断
19519726 MGI
acts upstream of or within muscle cell development IMP
IMP: 通过突变表型推断
20716577 MGI
acts upstream of or within muscle organ development IMP
IMP: 通过突变表型推断
26945058 MGI
acts upstream of or within muscle structure development IGI
IGI: 通过遗传相互作用推断
19293339 MGI
acts upstream of or within muscle system process IMP
IMP: 通过突变表型推断
24852368 MGI
acts upstream of or within myelination in peripheral nervous system IMP
IMP: 通过突变表型推断
24277578 MGI
acts upstream of or within nervous system process IMP
IMP: 通过突变表型推断
24277578 MGI
acts upstream of or within neuron apoptotic process IDA
IDA: 通过直接分析推断
21459131 MGI
acts upstream of or within organelle organization IMP
IMP: 通过突变表型推断
21037586 MGI
acts upstream of or within ossification IMP
IMP: 通过突变表型推断
19248115 MGI
acts upstream of or within peripheral nervous system development IMP
IMP: 通过突变表型推断
24277578 MGI
acts upstream of or within phosphatidylinositol 3-kinase/protein kinase B signal transduction IDA
IDA: 通过直接分析推断
21459131 MGI
acts upstream of or within phosphatidylinositol 3-kinase/protein kinase B signal transduction IMP
IMP: 通过突变表型推断
26565691 MGI
acts upstream of or within protein lipidation IMP
IMP: 通过突变表型推断
26565691 MGI
acts upstream of or within protein phosphorylation IMP
IMP: 通过突变表型推断
19114551 MGI
acts upstream of or within protein tetramerization IDA
IDA: 通过直接分析推断
23300779 MGI
acts upstream of or within reactive oxygen species metabolic process IMP
IMP: 通过突变表型推断
20716577 MGI
acts upstream of or within reduction of food intake in response to dietary excess IMP
IMP: 通过突变表型推断
19114551 MGI
acts upstream of or within regulation of cell size IMP
IMP: 通过突变表型推断
19114551 MGI
acts upstream of or within regulation of collagen fibril organization IMP
IMP: 通过突变表型推断
20951202 MGI
acts upstream of or within respiratory system process IMP
IMP: 通过突变表型推断
19114551 MGI
acts upstream of or within response to UV IDA
IDA: 通过直接分析推断
21459131 MGI
acts upstream of or within response to activity IMP
IMP: 通过突变表型推断
24357721 MGI
acts upstream of or within response to bleomycin IMP
IMP: 通过突变表型推断
25158062 MGI
acts upstream of or within response to decreased oxygen levels IMP
IMP: 通过突变表型推断
22343710 MGI
acts upstream of or within response to lipid IMP
IMP: 通过突变表型推断
23437220 MGI
acts upstream of or within response to lipopolysaccharide IMP
IMP: 通过突变表型推断
19114551 MGI
acts upstream of or within response to mechanical stimulus IMP
IMP: 通过突变表型推断
19248115 MGI
acts upstream of or within response to muscle activity IMP
IMP: 通过突变表型推断
22024752 MGI
acts upstream of or within response to pain IMP
IMP: 通过突变表型推断
24277578 MGI
acts upstream of or within response to peptide IMP
IMP: 通过突变表型推断
24852368 MGI
acts upstream of or within response to polyamine macromolecule IMP
IMP: 通过突变表型推断
26565691 MGI
acts upstream of or within response to reactive oxygen species IMP
IMP: 通过突变表型推断
20716577 MGI
acts upstream of or within response to toxic substance IMP
IMP: 通过突变表型推断
23437220 MGI
acts upstream of or within response to wounding IDA
IDA: 通过直接分析推断
25989472 MGI
acts upstream of or within response to wounding IMP
IMP: 通过突变表型推断
22343710 MGI
acts upstream of or within response to xenobiotic stimulus IMP
IMP: 通过突变表型推断
19519726 MGI
acts upstream of or within sensory perception of mechanical stimulus IMP
IMP: 通过突变表型推断
23437220 MGI
acts upstream of or within single fertilization IGI
IGI: 通过遗传相互作用推断
28604699 MGI
acts upstream of or within skeletal muscle fiber development IMP
IMP: 通过突变表型推断
21037586 MGI
acts upstream of or within skeletal muscle fiber differentiation IGI
IGI: 通过遗传相互作用推断
19293339 MGI
acts upstream of or within skeletal muscle organ development IMP
IMP: 通过突变表型推断
26565691 MGI
acts upstream of or within skeletal muscle tissue development IMP
IMP: 通过突变表型推断
19248115 MGI
acts upstream of or within skeletal muscle tissue growth IMP
IMP: 通过突变表型推断
28043812 MGI
acts upstream of or within skeletal muscle tissue regeneration IMP
IMP: 通过突变表型推断
28043812 MGI
acts upstream of or within skin development IMP
IMP: 通过突变表型推断
25158062 MGI
acts upstream of or within tissue remodeling IMP
IMP: 通过突变表型推断
22343710 MGI
acts upstream of or within transmission of nerve impulse IMP
IMP: 通过突变表型推断
24277578 MGI
acts upstream of or within tricarboxylic acid cycle IMP
IMP: 通过突变表型推断
23437220 MGI
acts upstream of or within uterus development IGI
IGI: 通过遗传相互作用推断
28604699 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in basement membrane IDA
IDA: 通过直接分析推断
31837950 MGI
is active in extracellular matrix IDA
IDA: 通过直接分析推断
19248115 MGI
located in extracellular matrix IDA
IDA: 通过直接分析推断
8806434 MGI
is active in extracellular matrix IMP
IMP: 通过突变表型推断
20951202 MGI
is active in intracellular vesicle IDA
IDA: 通过直接分析推断
24357721 MGI
is active in lysosome IDA
IDA: 通过直接分析推断
28604699 MGI
is active in myofibril IMP
IMP: 通过突变表型推断
20716577 MGI
located in sarcolemma IDA
IDA: 通过直接分析推断
16810681 MGI
is active in sarcoplasmic reticulum IMP
IMP: 通过突变表型推断
22024752 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

collagen alpha-1(VI) chain

procollagen, type VI, alpha 1

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS02992 COL6A1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19250 Col6a1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25739 Col6a1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Col6a1 NCBI NCBI:1291
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