2. Gene
  3. Coq7 - demethyl-Q 7 Gene

Coq7 - demethyl-Q 7 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: clk-1

基因 ID: 12850 | 基因类型: protein coding

关于 Coq7

功能概要

Predicted to enable 2-octoprenyl-3-methyl-6-methoxy-1,4-benzoquinone hydroxylase activity and chromatin binding activity. Acts upstream of or within several processes, including age-dependent response to oxidative stress; chordate embryonic development; and mitochondrion morphogenesis. Located in mitochondrion. Is expressed in several structures, including alimentary system; ear; nervous system; respiratory system; and skeleton. Human ortholog(s) of this gene implicated in primary coenzyme Q10 deficiency 8. Orthologous to human COQ7 (coenzyme Q7, hydroxylase). [provided by Alliance of Genome Resources, Apr 2022]

Coq7 基因产物(4)

mRNA Protein Name
NM_001304758.2 NP_001291687.1 5-demethoxyubiquinone hydroxylase, mitochondrial isoform 2
NM_001412267.1 NP_001399196.1 5-demethoxyubiquinone hydroxylase, mitochondrial isoform 3
NM_001412268.1 NP_001399197.1 5-demethoxyubiquinone hydroxylase, mitochondrial isoform 4
NM_009940.4 NP_034070.1 5-demethoxyubiquinone hydroxylase, mitochondrial isoform 1
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cellular response to oxidative stress IMP
IMP: 通过突变表型推断
18635541 MGI
acts upstream of or within determination of adult lifespan IMP
IMP: 通过突变表型推断
19478076 MGI
acts upstream of or within in utero embryonic development IMP
IMP: 通过突变表型推断
11585841 MGI
acts upstream of or within mitochondrial ATP synthesis coupled electron transport IMP
IMP: 通过突变表型推断
18635541 MGI
acts upstream of or within mitochondrion organization IMP
IMP: 通过突变表型推断
11716496 MGI
acts upstream of or within neural tube formation IMP
IMP: 通过突变表型推断
11716496 MGI
acts upstream of or within neurogenesis IMP
IMP: 通过突变表型推断
11716496 MGI
acts upstream of or within respiratory electron transport chain IMP
IMP: 通过突变表型推断
11585841 MGI
acts upstream of or within response to oxidative stress IGI
IGI: 通过遗传相互作用推断
19478076 MGI
acts upstream of or within response to oxidative stress IMP
IMP: 通过突变表型推断
19478076 MGI
NOT acts upstream of or within ubiquinone biosynthetic process IMP
IMP: 通过突变表型推断
19478076 MGI
acts upstream of or within ubiquinone biosynthetic process IMP
IMP: 通过突变表型推断
11585841 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

5-demethoxyubiquinone hydroxylase, mitochondrial

DMQ hydroxylase

coenzyme Q biosynthesis protein 7 homolog

timing protein clk-1 homolog

ubiquinone biosynthesis monooxygenase COQ7

ubiquinone biosynthesis protein COQ7 homolog

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-133033 COQ7-IN-1 Inhibitor 99.98% 否
HY-138429 COQ7-IN-2 Inhibitor 99.48% 否
HY-RS03043 COQ7 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18468 Coq7 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24949 Coq7 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Coq7 NCBI NCBI:10229
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