1. Gene
  2. OCSTAMP - osteoclast stimulatory transmembrane protein Gene

OCSTAMP - osteoclast stimulatory transmembrane protein Gene

中文名称:破骨细胞刺激跨膜蛋白

种属: Homo sapiens

同用名: OC-STAMP; C20orf123; dJ257E24.3

基因 ID: 128506 | 基因类型: protein coding

关于 OCSTAMP

This gene has 1 transcript (splice variant), 177 orthologues and 3 paralogues. Low expression observed in reference dataset.

功能概要

由该基因编码的蛋白质与小鼠破骨细胞刺激跨膜蛋白 (OCSTAMP) 同源,后者是一种促进破骨细胞成核的膜锚定细胞表面受体。小鼠蛋白还参与骨吸收和破骨细胞分化。[RefSeq 提供,2017 年 2 月]

The protein encoded by this gene is orthologous to the mouse osteoclast stimulatory transmembrane protein (OCSTAMP), which is a membrane-anchored cell surface receptor that promotes nucleation of osteoclasts. The mouse protein is also involved in bone resorption and osteoclast differentiation. [provided by RefSeq, Feb 2017]

OCSTAMP 基因产物(1)

mRNA Protein Name
NM_080721.3 NP_542452.1 osteoclast stimulatory transmembrane protein

OCSTAMP 蛋白结构

DC_STAMP

DC_STAMP: DC-STAMP-like protein (254 - 446)

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  • 566 a.a.
蛋白主名 其他名称

osteoclast stimulatory transmembrane protein

transmembrane protein C20orf123

关联疾病

疾病名称 别名
Osteopetrosis, Autosomal Recessive 8

Autosomal Recessive Osteopetrosis 8

OPTB8

Osteopetrosis, Autosomal Recessive, Type 8

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus OCSTAMP RGD RGD:1308620
Mus musculus OCSTAMP MGD MGI:1921864
Felis catus OCSTAMP VGNC VGNC:81135
Canis familiaris OCSTAMP VGNC VGNC:54657
Macaca mulatta OCSTAMP VGNC VGNC:75410
Bos taurus OCSTAMP VGNC VGNC:32399