1. Gene
  2. Cpox - coproporphyrinogen oxidase Gene

Cpox - coproporphyrinogen oxidase Gene

种属: Mus musculus

同用名: CPX; Cpo; HCP; cac; nct; M100835; Rgsc835

基因 ID: 12892 | 基因类型: protein coding

关于 Cpox

功能概要

Enables coproporphyrinogen oxidase activity. A structural constituent of eye lens. Acts upstream of or within heme biosynthetic process. Located in membrane and mitochondrion. Is expressed in embryo and yolk sac. Used to study hereditary coproporphyria. Human ortholog(s) of this gene implicated in hereditary coproporphyria and liver disease. Orthologous to human CPOX (coproporphyrinogen oxidase). [provided by Alliance of Genome Resources, Apr 2022]

Cpox 基因产物(1)

mRNA Protein Name
NM_007757.2 NP_031783.2 oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables coproporphyrinogen oxidase activity IDA
IDA: 通过直接分析推断
7607249 MGI
enables structural constituent of eye lens IMP
IMP: 通过突变表型推断
12470976 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in heme A biosynthetic process IDA
IDA: 通过直接分析推断
8407975 MGI
involved in heme B biosynthetic process IDA
IDA: 通过直接分析推断
8407975 MGI
involved in heme O biosynthetic process IDA
IDA: 通过直接分析推断
8407975 MGI
acts upstream of or within heme biosynthetic process IDA
IDA: 通过直接分析推断
8407975 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in membrane IMP
IMP: 通过突变表型推断
20080761 MGI
is active in mitochondrial intermembrane space IDA
IDA: 通过直接分析推断
8407975 MGI
located in mitochondrion IDA
IDA: 通过直接分析推断
8407975 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial

COX

Coproporphyrinogen III oxidase, mitochondrial precursor (Coproporphyrinogenase) (Coprogen oxidase) (COX)

clone 560

coprogen oxidase

coproporphyrinogen-III oxidase, mitochondrial

coproporphyrinogenase

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cpox NCBI NCBI:1371