COL16A1 - collagen type XVI alpha 1 chain Gene

中文名称：XVI 型胶原蛋白 alpha 1 链

种属: Homo sapiens

同用名: 447AA; FP1572

关于 COL16A1

功能概要

该基因编码 XVI 型胶原蛋白的 α 链，它是 FACIT 胶原蛋白家族的成员 (具有间断螺旋的原纤维相关胶原蛋白) 。该胶原蛋白家族的成员被发现与形成纤维的胶原蛋白如 I 型和 II 型相关，并用于维持细胞外基质的完整性。在成纤维细胞和角质形成细胞以及平滑肌和羊膜中发现了高水平的 XVI 型胶原蛋白。[RefSeq 提供，2008 年 7 月]

This gene encodes the alpha chain of type XVI collagen, a member of the FACIT collagen family (fibril-associated collagens with interrupted helices). Members of this collagen family are found in association with fibril-forming collagens such as type I and II, and serve to maintain the integrity of the extracellular matrix. High levels of type XVI collagen have been found in fibroblasts and keratinocytes, and in smooth muscle and amnion. [provided by RefSeq, Jul 2008]