2. Gene
  3. Cyp17a1 - cytochrome P450, family 17, subfamily a, polypeptide 1 Gene

Cyp17a1 - cytochrome P450, family 17, subfamily a, polypeptide 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Cyp17; p450c17

基因 ID: 13074 | 基因类型: protein coding

关于 Cyp17a1

功能概要

Enables steroid 17-alpha-monooxygenase activity. Acts upstream of or within glucocorticoid biosynthetic process. Located in axon and neuronal cell body. Is expressed in several structures, including adrenal gland; gut; nervous system; reproductive system; and retina layer. Human ortholog(s) of this gene implicated in several diseases, including cholelithiasis; congenital adrenal hyperplasia; gallbladder cancer; osteoporosis; and prostate Cancer. Orthologous to human CYP17A1 (Cytochrome P450 family 17 subfamily A member 1). [provided by Alliance of Genome Resources, Apr 2022]

Cyp17a1 基因产物(1)

mRNA Protein Name
NM_007809.3 NP_031835.3 steroid 17-alpha-hydroxylase/17,20 lyase precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables steroid 17-alpha-monooxygenase activity IDA
IDA: 通过直接分析推断
6090441 MGI
enables steroid 17-alpha-monooxygenase activity IMP
IMP: 通过突变表型推断
15169901 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in androgen biosynthetic process IDA
IDA: 通过直接分析推断
6090441 MGI
involved in androgen biosynthetic process IMP
IMP: 通过突变表型推断
15169901 MGI
acts upstream of or within glucocorticoid biosynthetic process IDA
IDA: 通过直接分析推断
7588219 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axon IDA
IDA: 通过直接分析推断
7588260 MGI
is active in endoplasmic reticulum IDA
IDA: 通过直接分析推断
26819663 MGI
is active in endoplasmic reticulum membrane IDA
IDA: 通过直接分析推断
26819663 MGI
located in neuronal cell body IDA
IDA: 通过直接分析推断
7588260 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

steroid 17-alpha-hydroxylase/17,20 lyase

17-alpha-hydroxyprogesterone aldolase

CYPXVII

cytochrome P450 17A1

cytochrome P450, 17

cytochrome P450, 17a1

cytochrome P450-C17

cytochrome P450c17

steroid 17-alpha hydroxylase

steroid 17-alpha-monooxygenase

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-163359 CYP17A1/HDAC6-IN-1 Inhibitor / 否
HY-164457 ASN-001 Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cyp17a1 NCBI NCBI:1586
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