2. Gene
  3. Cyp1a2 - cytochrome P450, family 1, subfamily a, polypeptide 2 Gene

Cyp1a2 - cytochrome P450, family 1, subfamily a, polypeptide 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: CP12; CYPIA2; P450-3

基因 ID: 13077 | 基因类型: protein coding

关于 Cyp1a2

功能概要

Enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen. Acts upstream of or within several processes, including cellular response to cadmium ion; dibenzo-p-dioxin metabolic process; and hydrogen peroxide biosynthetic process. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be active in intracellular membrane-bounded organelle. Is expressed in liver. Human ortholog(s) of this gene implicated in breast cancer; chronic obstructive pulmonary disease; endometrial cancer; and porphyria cutanea tarda. Orthologous to human CYP1A2 (Cytochrome P450 family 1 subfamily A member 2). [provided by Alliance of Genome Resources, Apr 2022]

Cyp1a2 基因产物(1)

mRNA Protein Name
NM_009993.3 NP_034123.1 cytochrome P450 1A2
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen IDA
IDA: 通过直接分析推断
8274012 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cellular respiration IMP
IMP: 通过突变表型推断
7761462 MGI
acts upstream of or within cellular response to cadmium ion IDA
IDA: 通过直接分析推断
16183037 MGI
acts upstream of or within dibenzo-p-dioxin metabolic process IMP
IMP: 通过突变表型推断
9240455 MGI
acts upstream of or within hydrogen peroxide biosynthetic process IMP
IMP: 通过突变表型推断
14980704 MGI
acts upstream of or within lung development IMP
IMP: 通过突变表型推断
7761462 MGI
acts upstream of or within porphyrin-containing compound metabolic process IMP
IMP: 通过突变表型推断
9461503 MGI
acts upstream of or within post-embryonic development IMP
IMP: 通过突变表型推断
7761462 MGI
acts upstream of or within regulation of gene expression IMP
IMP: 通过突变表型推断
12438513 MGI
acts upstream of or within toxin metabolic process IMP
IMP: 通过突变表型推断
17166882 MGI
acts upstream of or within xenobiotic metabolic process IMP
IMP: 通过突变表型推断
8643688 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

cytochrome P450 1A2

cholesterol 25-hydroxylase

cytochrome P450 family 1 subfamily a polypeptide 1

cytochrome P450, 1a2, aromatic compound inducible

cytochrome P450-P2

cytochrome P450-P3

hydroperoxy icosatetraenoate dehydratase

相关产品

Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-132845 Utreloxastat Inhibitor 99.69% Phase 2
Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-170846 FGFRs-IN-1 Inhibitor / 否
HY-174417 NNRT-IN-10 Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cyp1a2 NCBI NCBI:1544
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