2. Gene
  3. Cyp27b1 - cytochrome P450, family 27, subfamily b, polypeptide 1 Gene

Cyp27b1 - cytochrome P450, family 27, subfamily b, polypeptide 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Vdr; Cp2b; Cyp1; Pddr; Vdd1; Vddr; Cyp40; VddrI; Cyp27b; P450c1

基因 ID: 13115 | 基因类型: protein coding

关于 Cyp27b1

功能概要

Enables calcidiol 1-monooxygenase activity. Involved in calcitriol biosynthetic process from calciol; response to vitamin D; and vitamin D catabolic process. Acts upstream of or within calcium ion transport. Located in mitochondrion. Is expressed in several structures, including lower jaw molar; metanephros; and testis. Used to study rickets. Human ortholog(s) of this gene implicated in hepatitis B; obesity; rickets; type 1 diabetes mellitus; and vitamin D-dependent rickets type 1A. Orthologous to human CYP27B1 (Cytochrome P450 family 27 subfamily B member 1). [provided by Alliance of Genome Resources, Apr 2022]

Cyp27b1 基因产物(1)

mRNA Protein Name
NM_010009.2 NP_034139.2 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables calcidiol 1-monooxygenase activity IDA
IDA: 通过直接分析推断
9295274 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in calcitriol biosynthetic process from calciol IDA
IDA: 通过直接分析推断
15972816 MGI
acts upstream of or within calcium ion transport IMP
IMP: 通过突变表型推断
12205031 MGI
involved in response to vitamin D IDA
IDA: 通过直接分析推断
9295274 MGI
involved in vitamin D catabolic process IDA
IDA: 通过直接分析推断
9295274 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial

1alpha(OH)ase

25(OH)D 1alpha-hydroxylase

25-OHD-1 alpha-hydroxylase

25-hydroxyvitamin D(3) 1-alpha-hydroxylase

25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial precursor (25-OHD-1 alpha-hydroxylase) (25-hydroxyvitamin D3 1-alpha-hydroxylase) (VD

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03451 CYP27B1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS16287 Cyp27b1 Mouse Pre-designed siRNA Set A / 否
HY-RS25766 Cyp27b1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cyp27b1 NCBI NCBI:1594
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