Cyp7b1 - cytochrome P450, family 7, subfamily b, polypeptide 1 Gene

种属: Mus musculus

同用名: hct-1; D3Ertd552e

关于 Cyp7b1

功能概要

Enables oxysterol 7-alpha-hydroxylase activity. Involved in B cell chemotaxis and bile acid biosynthetic process. Acts upstream of or within negative regulation of intracellular Estrogen receptor signaling pathway; positive regulation of epithelial cell proliferation; and prostate gland epithelium morphogenesis. Predicted to be located in intracellular membrane-bounded organelle. Is expressed in several structures, including alimentary system; brain; genitourinary system; limb; and sensory organ. Human ortholog(s) of this gene implicated in congenital bile acid synthesis defect 3 and hereditary spastic paraplegia 5A. Orthologous to human CYP7B1 (Cytochrome P450 family 7 subfamily B member 1). [provided by Alliance of Genome Resources, Apr 2022]