2. Gene
  3. Daxx - Fas death domain-associated protein Gene

Daxx - Fas death domain-associated protein Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

基因 ID: 13163 | 基因类型: protein coding

关于 Daxx

功能概要

Enables histone binding activity and transcription coactivator activity. Involved in nucleosome assembly; positive regulation of transcription by RNA polymerase II; and protein localization to chromatin. Acts upstream of or within several processes, including apoptotic signaling pathway; negative regulation of transcription, DNA-templated; and regulation of apoptotic process. Located in PML body and cytosol. Colocalizes with heterochromatin. Is expressed in several structures, including brain; genitourinary system; heart; hemolymphoid system gland; and liver. Human ortholog(s) of this gene implicated in islet cell tumor and ovary epithelial Cancer. Orthologous to human DAXX (death domain associated protein). [provided by Alliance of Genome Resources, Apr 2022]

Daxx 基因产物(3)

mRNA Protein Name
NM_001199733.1 NP_001186662.1 death domain-associated protein 6
NM_001355704.1 NP_001342633.1 death domain-associated protein 6
NM_007829.4 NP_031855.3 death domain-associated protein 6
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables histone binding IDA
IDA: 通过直接分析推断
20211137 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
9215629 MGI
enables transcription coactivator activity IDA
IDA: 通过直接分析推断
11799127 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within apoptotic signaling pathway IGI
IGI: 通过遗传相互作用推断
12917339 MGI
involved in cell population proliferation IGI
IGI: 通过遗传相互作用推断
15781341 MGI
acts upstream of or within mitotic cytokinesis IMP
IMP: 通过突变表型推断
15252119 MGI
acts upstream of or within negative regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
12529400 MGI
acts upstream of or within negative regulation of apoptotic process IMP
IMP: 通过突变表型推断
10444590 MGI
involved in nucleosome assembly IMP
IMP: 通过突变表型推断
20651253 MGI
acts upstream of or within positive regulation of apoptotic signaling pathway IDA
IDA: 通过直接分析推断
10684855 MGI
acts upstream of or within positive regulation of apoptotic signaling pathway IGI
IGI: 通过遗传相互作用推断
10684855 MGI
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
22500635 MGI
involved in protein localization to chromatin IMP
IMP: 通过突变表型推断
17081986 MGI
acts upstream of or within regulation of multicellular organism growth IMP
IMP: 通过突变表型推断
10444590 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in PML body IDA
IDA: 通过直接分析推断
10684855 MGI
located in cytosol IDA
IDA: 通过直接分析推断
10684855 MGI
colocalizes with heterochromatin IDA
IDA: 通过直接分析推断
17081986 MGI
located in heterochromatin IDA
IDA: 通过直接分析推断
15252119 MGI
located in nucleus IDA
IDA: 通过直接分析推断
10444590 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

death domain-associated protein 6

death-domain associated protein

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03535 DAXX Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19318 Daxx Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25809 Daxx Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Daxx NCBI NCBI:1616
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