1. Gene
  2. Dbnl - drebrin-like Gene

Dbnl - drebrin-like Gene

种属: Mus musculus

同用名: Abp1; SH3P7; mAbp1

基因 ID: 13169 | 基因类型: protein coding

关于 Dbnl

功能概要

Enables actin filament binding activity and protein domain specific binding activity. Involved in neuron projection morphogenesis; podosome assembly; and synapse assembly. Acts upstream of or within Rac protein signal transduction. Located in several cellular components, including lamellipodium; podosome; and ruffle. Is expressed in several structures, including central nervous system; genitourinary system; liver; retina; and spleen. Orthologous to human DBNL (drebrin like). [provided by Alliance of Genome Resources, Apr 2022]

Dbnl 基因产物(3)

mRNA Protein Name
NM_001146308.1 NP_001139780.1 drebrin-like protein isoform 1
NM_001146309.1 NP_001139781.1 drebrin-like protein isoform 3
NM_013810.3 NP_038838.1 drebrin-like protein isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables actin binding IDA
IDA: 通过直接分析推断
10637315 MGI
enables actin filament binding IDA
IDA: 通过直接分析推断
10637315 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
12913069 MGI
enables protein domain specific binding IDA
IDA: 通过直接分析推断
9630982 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within Rac protein signal transduction IDA
IDA: 通过直接分析推断
10637315 MGI
NOT acts upstream of or within actin filament bundle assembly IDA
IDA: 通过直接分析推断
10637315 MGI
NOT acts upstream of or within actin filament severing IDA
IDA: 通过直接分析推断
10637315 MGI
NOT acts upstream of or within barbed-end actin filament capping IDA
IDA: 通过直接分析推断
10637315 MGI
involved in neuron projection morphogenesis IMP
IMP: 通过突变表型推断
18829961 MGI
involved in podosome assembly IMP
IMP: 通过突变表型推断
22303001 MGI
involved in synapse assembly IMP
IMP: 通过突变表型推断
18829961 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell cortex IDA
IDA: 通过直接分析推断
12913069 MGI
located in cytoplasm IDA
IDA: 通过直接分析推断
10637315 MGI
located in lamellipodium IDA
IDA: 通过直接分析推断
10637315 MGI
located in podosome IDA
IDA: 通过直接分析推断
22303001 MGI
located in ruffle IDA
IDA: 通过直接分析推断
12913069 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

drebrin-like protein

SH3 domain-containing protein 7

actin-binding protein 1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Dbnl NCBI NCBI:28988