1. Gene
  2. Defb1 - defensin beta 1 Gene

Defb1 - defensin beta 1 Gene

种属: Mus musculus

同用名: BD-1

基因 ID: 13214 | 基因类型: protein coding

关于 Defb1

功能概要

Predicted to enable CCR6 Chemokine Receptor binding activity and identical protein binding activity. Involved in innate immune response and response to bacterium. Predicted to be located in microvesicle and sperm midpiece. Predicted to be extrinsic component of membrane. Predicted to be active in extracellular space. Is expressed in epidermis and skin. Human ortholog(s) of this gene implicated in asthma; chronic obstructive pulmonary disease; and lung disease. Orthologous to human DEFB1 (defensin beta 1). [provided by Alliance of Genome Resources, Apr 2022]

Defb1 基因产物(1)

mRNA Protein Name
NM_007843.3 NP_031869.1 beta-defensin 1 precursor
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in innate immune response IMP
IMP: 通过突变表型推断
12010999 MGI
involved in response to bacterium IMP
IMP: 通过突变表型推断
12010999 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

beta-defensin 1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Defb1 NCBI NCBI:1672
Rattus norvegicus Defb1 NCBI NCBI:83687